Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Maxime Zamba-Campero *Division of Molecular and Cellular Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, 20892, USA.
Daniel Soliman *Division of Molecular and Cellular Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, 20892, USA.ORCID 0000-0001-8380-2970
Huaxin YuDepartment of Microbial Pathogenesis, Yale School of Medicine, New Haven, CT, 06536, USA.
Amanda G LasseterDivision of Immunity and Pathogenesis, Burnett School of Biomedical Sciences, University of Central Florida College of Medicine, Orlando, FL, 32827, USA.
Yuen-Yan ChangDivision of Molecular and Cellular Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, 20892, USA.ORCID 0000-0003-4952-8941
Julia L SilbermanDivision of Molecular and Cellular Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, 20892, USA.ORCID 0009-0007-6802-2002
Jun LiuDepartment of Microbial Pathogenesis, Yale School of Medicine, New Haven, CT, 06536, USA.ORCID 0000-0003-3108-6735
L AravindDivision of Intramural Research, National Library of Medicine, National Institutes of Health, Bethesda, MD, 20894, USA.
Mollie W JewettDivision of Immunity and Pathogenesis, Burnett School of Biomedical Sciences, University of Central Florida College of Medicine, Orlando, FL, 32827, USA.ORCID 0000-0003-3130-3795
Gisela StorzDivision of Molecular and Cellular Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, 20892, USA.ORCID 0000-0001-6698-1241
Philip P AdamsDivision of Molecular and Cellular Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, 20892, USA. philip.adams@nih.gov.ORCID 0000-0002-2575-6328
Funding
Evolutionary Analysis and Comparative Genomics of Protein SuperfamiliesZIALM594244 · NLM · NATIONAL LIBRARY OF MEDICINE · PI ARAVIND, L · 2009 to 2025
$20.3M
Small Regulatory RNAsZIAHD001608 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI STORZ, GISELA · 2009 to 2025
$16.9M
Structure-Function Relationships in the Spirochetal Flagellar MotorR01AI087946 · NIAID · YALE UNIVERSITY · PI LIU, JUN · 2010 to 2025
$6.6M
Determination of the genetic basis for B. burgdorferi mammalian infectivityR01AI099094 · NIAID · UNIVERSITY OF CENTRAL FLORIDA · PI Mollie W Jewett · 2013 to 2026
$4.0M
Delineation of unique flagellar proteins in spirochetesR01AI132818 · NIAID · EAST CAROLINA UNIVERSITY · PI Jun Liu, MD A MOTALEB · 2018 to 2026
$3.3M
RNA-mediated gene regulation in the Lyme disease pathogenZIAHD008995 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI ADAMS, PHILIP · 2021 to 2025
$2.0M
High-throughput electron cryo-microscopeS10OD023603 · OD · YALE UNIVERSITY · PI SIGWORTH, FREDERICK J · 2018 to 2018
$1.9M
RNA-mediated gene regulation of the Lyme disease pathogenFI2GM133345 · NIGMS · U.S. NATIONAL INST/CHILD HLTH/HUMAN DEV · PI ADAMS, PHILIP P · 2019 to 2019
–
Intramural NIH HHS ZIA HD001608Intramural NIH HHS ZIA HD008995Intramural NIH HHS ZIA LM594244NIAID NIH HHS R01 AI087946NIAID NIH HHS R01 AI099094NIAID NIH HHS R01 AI132818NIGMS NIH HHS FI2 GM133345NIH HHS S10 OD023603U.S. Department of Health & Human Services | National Institutes of Health (NIH) 1Fi2GM133345U.S. Department of Health & Human Services | National Institutes of Health (NIH) 1ZIAHD008995
6 · The paper itself
Abstract
Flagella propel pathogens through their environments, yet are expensive to synthesize and are immunogenic. Thus, complex hierarchical regulatory networks control flagellar gene expression. Spirochetes are highly motile bacteria, but peculiarly, the archetypal flagellar regulator σ
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Broadly conserved FlgV controls flagellar assembly and Borrelia burgdorferi dissemination in mice. · full record | OpenQuestion