Evidence map›Paper›PMID 39614012›Full record

ArticleInsights into imaging2024

Ultra-high gradient performance 3-Tesla MRI for super-fast and high-quality prostate imaging: initial experience.

Leon M Bischoff, Christoph Endler, Philipp Krausewitz, Joerg Ellinger, Niklas Klümper, Alexander Isaak, Narine Mesropyan, Dmitrij Kravchenko, Sebastian Nowak, Daniel Kuetting and 5 more

Registry-linked trialAbstract read
In one paragraph

Article in Insights into imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06244680 (Super-fast 3T Prostate MRI Using High Gradient Strength and Deep Learning), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06244680 completednot on this map

Super-fast 3T Prostate MRI Using High Gradient Strength and Deep Learning: Initial Experience

TypeobservationalSponsorUniversity Hospital, BonnRan2023 to 2023Enrolled77ConditionsProstate CancerArmsMRI of the prostate
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Leon M BischoffDepartment of Diagnostic and Interventional Radiology, University Hospital Bonn, Bonn, Germany.
Christoph EndlerDepartment of Diagnostic and Interventional Radiology, University Hospital Bonn, Bonn, Germany.
Philipp KrausewitzDepartment of Urology, University Hospital Bonn, Bonn, Germany.
Joerg EllingerDepartment of Urology, University Hospital Bonn, Bonn, Germany.
Niklas KlümperDepartment of Urology, University Hospital Bonn, Bonn, Germany.
Alexander IsaakDepartment of Diagnostic and Interventional Radiology, University Hospital Bonn, Bonn, Germany.
Narine MesropyanDepartment of Diagnostic and Interventional Radiology, University Hospital Bonn, Bonn, Germany.
Dmitrij KravchenkoDepartment of Diagnostic and Interventional Radiology, University Hospital Bonn, Bonn, Germany.
Sebastian NowakDepartment of Diagnostic and Interventional Radiology, University Hospital Bonn, Bonn, Germany.
Daniel KuettingDepartment of Diagnostic and Interventional Radiology, University Hospital Bonn, Bonn, Germany.
Alois M SprinkartDepartment of Diagnostic and Interventional Radiology, University Hospital Bonn, Bonn, Germany.
Petra MürtzDepartment of Diagnostic and Interventional Radiology, University Hospital Bonn, Bonn, Germany.
Claus C PieperDepartment of Diagnostic and Interventional Radiology, University Hospital Bonn, Bonn, Germany.
Ulrike AttenbergerDepartment of Diagnostic and Interventional Radiology, University Hospital Bonn, Bonn, Germany.
Julian A LuetkensDepartment of Diagnostic and Interventional Radiology, University Hospital Bonn, Bonn, Germany. julian.luetkens@ukbonn.de.ORCID http://orcid.org/0000-0002-7715-4636

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo implement and evaluate a super-fast and high-quality biparametric MRI (bpMRI) protocol for prostate imaging acquired at a new ultra-high gradient 3.0-T MRI system.

methodsParticipants with clinically suspected prostate cancer prospectively underwent a multiparametric MRI (mpMRI) on a new 3.0-T MRI scanner (maximum gradient strength: 200 mT/m, maximum slew rate: 200 T/m/s). The bpMRI protocol was extracted from the full mpMRI protocol, including axial T2-weighted and diffusion-weighted (DWI) sequences (b0/800, b1500). Overall image quality was rated by two readers on a five-point Likert scale from (1) non-diagnostic to (5) excellent. PI-RADS 2.1 scores were assessed by three readers separately for the bpMRI and mpMRI protocols. Cohen's and Fleiss' κ were calculated for PI-RADS agreement between protocols and interrater reliability between readers, respectively.

resultsSeventy-seven male participants (mean age, 66 ± 8 years) were included. Acquisition time of the bpMRI protocol was reduced by 62% (bpMRI: 5 min, 33 ± 21 s; mpMRI: 14 min, 50 ± 42 s). The bpMRI protocol showed excellent overall image quality for both the T2-weighted (median score both readers: 5 [IQR: 4-5]) and DWI (b1500) sequence (median score reader 1: 4 [IQR: 4-5]; reader 2: 4 [IQR: 4-4]). PI-RADS score agreement between protocols was excellent (Cohen's κ range: 0.91-0.95 [95% CI: 0.89, 0.99]) with an overall good interrater reliability (Fleiss' κ, 0.86 [95% CI: 0.80, 0.92]).

conclusionUltra-high gradient MRI allows the establishment of a high-quality and rapidly acquired bpMRI with high PI-RADS agreement to a full mpMRI protocol. TRIALS REGISTRATION: Clinicaltrials.gov, NCT06244680, Registered 06 February 2024, retrospectively registered, https://classic. CLINICALTRIALS: gov/ct2/show/NCT06244680 . CRITICAL RELEVANCE STATEMENT: A novel 3.0-Tesla MRI system with an ultra-high gradient performance enabled high-quality biparametric prostate MRI in 5.5 min while achieving excellent PI-RADS agreement with a standard multiparametric protocol. KEY POINTS: Multi- and biparametric prostate MRIs were prospectively acquired utilizing a maximum gradient of 200 mT/m. Super-fast biparametric MRIs showed excellent image quality and had high PI-RADS agreement with multiparametric MRIs. Implementation of high gradient MRI in clinical routine allows accelerated and high-quality biparametric prostate examinations.

Indexed as

Biparametric MRIMultiparametric MRIPI-RADSProstate cancerUltra-high gradient strength

Identifiers

PMID39614012
PMCPMC11607256

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.