Evidence map›Paper›PMID 39613998›Full record

ArticleBiotechnology letters2024

Coupling ultrasound and membrane filtration for the fractionation of Spirulina platensis sp. and the recovery of phycocyanin and pigment-free proteins.

Sara Obeid, Hussein Rida, Jérôme Peydecastaing, Hosni Takache, Ali Ismail, Pierre-Yves Pontalier

Abstract read
In one paragraph

Article in Biotechnology letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Ultrasound-Assisted Extraction of Bioactives fromFoods (Basel, Switzerland) · 2025
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sara ObeidLaboratoire de Chimie Agro-Industrielle (LCA), Université de Toulouse, Toulouse INP, INRAE, France.
Hussein RidaLaboratoire de Chimie Agro-Industrielle (LCA), Université de Toulouse, Toulouse INP, INRAE, France.ORCID http://orcid.org/0009-0004-1610-9964
Jérôme PeydecastaingLaboratoire de Chimie Agro-Industrielle (LCA), Université de Toulouse, Toulouse INP, INRAE, France.
Hosni TakacheDépartement des Sciences et Technologies Alimentaires, Faculté d'Agronomie, Université Libanaise, Dekwaneh, Lebanon.
Ali IsmailDépartement des Sciences et Technologies Alimentaires, Faculté d'Agronomie, Université Libanaise, Dekwaneh, Lebanon.
Pierre-Yves PontalierLaboratoire de Chimie Agro-Industrielle (LCA), Université de Toulouse, Toulouse INP, INRAE, France. Pierreyves.pontalier@ensiacet.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cyanobacterium Spirulina platensis was subjected to a fractionation process involving ultrasound-assisted extraction and membrane filtration to obtain a pure phycocyanin fraction and a clarified colorless protein fraction free of chlorophyll and carotenoids. The effects of pressure and power on total protein release were assessed. The retention of the extracted proteins was then assessed by ultrafiltration, with and without ammonium sulfate precipitation. Total protein recovery yields reached 97% in aqueous solution, at a low frequency (12 kHz), atmospheric pressure, and with an ultrasonic power of 200 Watts (W). Ammonium sulfate (25% w/v) precipitation was used to remove pigments and impurities from the crude protein extract. Finally, semi-frontal ultrafiltration resulted in high levels of C-phycocyanin recovery in the retentate: 95% and 91% with 10 and 100 kDa-cutoff membranes, respectively. However, the levels of total non-pigmented proteins in the permeate compartment did not exceed 67% with a 100 kDa-cutoff membrane. A fractionation process is proposed here for the valorization of two different protein fractions from Spirulina platensis.

Indexed as

PhycocyaninSpirulinaUltrafiltrationBacterial ProteinsChemical FractionationFiltrationBacterial ProteinsPhycocyaninMembrane processMicroalgaePhycocyaninProtein purificationSonoextraction

Identifiers

PMID39613998
PMCPMC11607054

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.