Evidence map›Paper›PMID 39613981›Full record

ArticleInsights into imaging2024

Impact of uncertainty quantification through conformal prediction on volume assessment from deep learning-based MRI prostate segmentation.

Marius Gade, Kevin Mekhaphan Nguyen, Sol Gedde, Alvaro Fernandez-Quilez

Abstract read
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Article in Insights into imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marius GadeDepartment of Electrical Engineering and Computer Science, University of Stavanger, Stavanger, Norway.
Kevin Mekhaphan NguyenDepartment of Electrical Engineering and Computer Science, University of Stavanger, Stavanger, Norway.
Sol GeddeStavanger Medical Imaging Laboratory (SMIL), Department of Radiology, Stavanger University Hospital, Stavanger, Norway.
Alvaro Fernandez-QuilezDepartment of Electrical Engineering and Computer Science, University of Stavanger, Stavanger, Norway. alvaro.f.quilez@uis.no.ORCID http://orcid.org/0000-0001-7544-0797

Funding

Stavanger Universitetssjukehus F-12604
6 · The paper itself

Abstract

objectivesTo estimate the uncertainty of a deep learning (DL)-based prostate segmentation algorithm through conformal prediction (CP) and to assess its effect on the calculation of the prostate volume (PV) in patients at risk of prostate cancer (PC).

methodsThree-hundred seventy-seven multi-center 3-Tesla axial T2-weighted exams from biopsied males (66.64

resultsConformal prediction significantly reduced RVD when compared to the DL algorithm (RVD = - 2.81

conclusionUncertainty quantification through CP increases the accuracy and reliability of DL-based PV assessment in patients at risk of PC. CRITICAL RELEVANCE STATEMENT: Conformal prediction can flag uncertain pixel predictions of DL-based prostate MRI segmentation at a desired confidence level, increasing the reliability and safety of prostate volume assessment in patients at risk of prostate cancer. KEY POINTS: Conformal prediction can flag uncertain pixel predictions of prostate segmentations at a user-defined confidence level. Deep learning with conformal prediction shows high accuracy in prostate volumetric assessment. Agreement between automatic and ellipsoid-derived volume was significantly larger with conformal prediction.

Indexed as

Conformal predictionDeep learningMagnetic resonance imagingProstateUncertainty

Identifiers

PMID39613981
PMCPMC11607187

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.