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ArticleCurrent microbiology2024

Whole-Genome Analysis of Multidrug-Resistant Klebsiella pneumoniae Kp04 Reveals Distinctive Antimicrobial and Arsenic-Resistance Genomic Features: A Case Study from Bangladesh.

Md Javed Foysal, Farhana Momtaz, A M Masudul Azad Chowdhury, Afroza Akter Tanni, Asma Salauddin, Md Zahid Hasan, Sohana Akter Mina, Nahid Sultana, Sanjoy Kanti Biswas, Kamrul Islam and 2 more

Abstract read
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Article in Current microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Md Javed FoysalDepartment of Genetic Engineering and Biotechnology, Shahjalal University of Science and Technology, Sylhet, Bangladesh.ORCID http://orcid.org/0000-0002-2064-8897
Farhana MomtazCollege of Science, Health, Engineering and Education, Murdoch University, Perth, WA, Australia.ORCID http://orcid.org/0000-0002-8358-1909
A M Masudul Azad ChowdhuryDepartment of Genetic Engineering and Biotechnology, University of Chittagong, Chattogram, Bangladesh.ORCID http://orcid.org/0000-0002-1675-5075
Afroza Akter TanniDepartment of Genetic Engineering and Biotechnology, University of Chittagong, Chattogram, Bangladesh.ORCID http://orcid.org/0000-0003-3126-1054
Asma SalauddinDepartment of Genetic Engineering and Biotechnology, University of Chittagong, Chattogram, Bangladesh.
Md Zahid HasanDepartment of Genetic Engineering and Biotechnology, University of Chittagong, Chattogram, Bangladesh.ORCID http://orcid.org/0000-0002-6229-8725
Sohana Akter MinaDepartment of Genetic Engineering and Biotechnology, University of Chittagong, Chattogram, Bangladesh.
Nahid SultanaDepartment of Microbiology, Chattogram Maa O Shishu Hospital, Agrabad, Chattogram, Bangladesh.
Sanjoy Kanti BiswasDepartment of Microbiology, Chattogram Maa O Shishu Hospital, Agrabad, Chattogram, Bangladesh.
Kamrul IslamDepartment of Genetic Engineering and Biotechnology, Shahjalal University of Science and Technology, Sylhet, Bangladesh.
Alfred TayHelicobacter Research Laboratory, The Marshall Centre, University of Western Australia, Perth, WA, Australia.ORCID http://orcid.org/0000-0001-9705-4010
Adnan MannanDepartment of Genetic Engineering and Biotechnology, University of Chittagong, Chattogram, Bangladesh. adnan.mannan@cu.ac.bd.ORCID http://orcid.org/0000-0003-4070-9586

Funding

Research and Publication Cell, University of Chittagong 504-CU-RPC-2023-24/34/2024
6 · The paper itself

Abstract

Multidrug-resistant bacteria, particularly extended-spectrum-beta-lactamase-producing (ESBL) bacteria, pose a significant global public health challenge. Klebsiella pneumoniae (KPN) is frequently implicated in cases of this resistance. This study aimed to investigate the presence of drug and metal resistance genes in clinical K. pneumoniae isolate Kp04 and comparative genomics of clinical KPN isolates characterized from Bangladesh. A total of 12 isolates were collected. Disk-diffusion assay showed that all five isolates were resistant to 14 out of 21 tested antibiotics and sensitive to only three-tigecycline, imipenem, and meropenem. KPN Kp04 was positive for both bla

Indexed as

Anti-Bacterial AgentsDrug Resistance, Multiple, BacterialGenome, BacterialKlebsiella InfectionsKlebsiella pneumoniaeWhole Genome SequencingArsenicBangladeshbeta-LactamasesGenomicsHumansMicrobial Sensitivity TestsAnti-Bacterial AgentsArsenicbeta-Lactamases

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.