ArticleNature communications2024
Paired analysis of host and pathogen genomes identifies determinants of human tuberculosis.
Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The trial behind it
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Who cites it
15 citing papers in PubMed.
- Human Genetic Variation Associates With Infection by Derived Ugandan M. tuberculosis Lineage.The Journal of infectious diseases · 2026Article
- Immortal genome assumption significantly underestimates replication and death rates ofMicrobiology spectrum · 2026Article
- Immortal genome assumption significantly underestimates replication and death rates ofbioRxiv : the preprint server for biology · 2026Article
- HowVaccines · 2026Review
- Protection against reinfection with Mycobacterium tuberculosis extends across heterologous Mtb lineages.Mucosal immunology · 2026Article
- A co-evolutionary perspective on humans andeLife · 2026Review
- Membrane microdomains are crucial forScience advances · 2026Article
- The evolution of Mycobacterium tuberculosis as humans migrated out of Africa.Nature reviews. Genetics · 2026Article
- Spatiotemporal patterns of prevalence and mortality from respiratory infections and tuberculosis across Japan and its prefectures.PloS one · 2026Article
- Cross-continental transmission and host adaptation ofiMetaOmics · 2025Article
- Genomic landscape ofNew microbes and new infections · 2025Article
- Article
- Article
- Ecology, global diversity and evolutionary mechanisms in the Mycobacterium tuberculosis complex.Nature reviews. Microbiology · 2025Review
- Genome-to-genome analysis reveals associations between human and mycobacterial genetic variation in tuberculosis patients from Tanzania.BMC medical genomics · 2025Article
Corrections and comments
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Authors and funding
19 authors.
Funding
Abstract
Infectious disease is the result of interactions between host and pathogen and can depend on genetic variations in both. We conduct a genome-to-genome study of paired human and Mycobacterium tuberculosis genomes from a cohort of 1556 tuberculosis patients in Lima, Peru. We identify an association between a human intronic variant (rs3130660, OR = 10.06, 95%CI: 4.87 - 20.77, P = 7.92 × 10
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Registered trials
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