Evidence map›Paper›PMID 39613339›Full record

ArticleAmerican journal of human biology : the official journal of the Human Biology Council2025

Somatic Symptoms Are Associated With Elevated Blood Pressure and Epstein-Barr Virus Antibodies Among Shuar of the Ecuadorian Amazon.

Paula S Tallman, Rebecca A Seligman, Felicia C Madimenos, Melissa A Liebert, Tara J Cepon-Robins, J Josh Snodgrass, Thomas W McDade, Lawrence S Sugiyama

Abstract read
In one paragraph

Article in American journal of human biology : the official journal of the Human Biology Council, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. The Shuar Health and Life History Project: Overview at 20 Years and Introduction to the Special Issue.American journal of human biology : the official journal of the Human Biology Council · 2026
    Article
  2. Circulating Epstein-Barr Virus Antibody Levels as a Biomarker of Socioecological Adversity in Amazonian Ecuador.American journal of human biology : the official journal of the Human Biology Council · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Paula S TallmanDepartment of Anthropology, Loyola University Chicago, Chicago, Illinois, USA.
Rebecca A SeligmanDepartment of Anthropology, Northwestern University, Evanston, Illinois, USA.
Felicia C MadimenosQueens College, City University of New York, New York, New York, USA.ORCID 0000-0001-5442-232X
Melissa A LiebertDepartment of Anthropology, Northern Arizona University, Flagstaff, Arizona, USA.ORCID 0000-0001-8013-6773
Tara J Cepon-RobinsDepartment of Anthropology, University of Colorado, Boulder, Colorado, USA.ORCID 0000-0002-4508-8507
J Josh SnodgrassDepartment of Anthropology, University of Oregon, Eugene, Oregon, USA.ORCID 0000-0002-7021-777X
Thomas W McDadeDepartment of Anthropology, Northwestern University, Evanston, Illinois, USA.ORCID 0000-0001-5829-648X
Lawrence S SugiyamaDepartment of Anthropology, Northern Arizona University, Flagstaff, Arizona, USA.

Funding

NIH Director's Pioneer Award (RMI)DP1OD000516 · OD · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI COSMIDES, LEDA · 2005 to 2009
$3.6M
Leakey FoundationNational Science Foundation BCS-1027687National Science Foundation Graduate Research Fellowship ProgramNIH HHS #5DP1OD000516NIH HHS DP1 OD000516Northwestern UniversityUniversity of OregonWenner-Gren Foundation 7970
6 · The paper itself

Abstract

introductionThis study tests the hypothesis that self-reported somatic symptoms are associated with biomarkers of stress, including elevated blood pressure and suppressed immune function, among Shuar adults living in the Ecuadorian Amazon.

methodsResearch was conducted in three Shuar communities in the Upano Valley of the Ecuadorian Amazon and included the collection of biomarkers and a structured morbidity interview. Participants self-reported somatic symptoms such as headaches, body pain, fatigue, and other bodily symptoms. We examined whether the number of somatic symptoms reported was associated with measures of immune (Epstein-Barr virus [EBV] antibodies) and cardiovascular (blood pressure) functioning in 97 Shuar adults (37 women, 60 men; ages 18-65 years). Multivariate linear regression analyses were used to examine the relationships among somatic symptoms and stress biomarkers, controlling for age, sex, body mass index (BMI), active infection, level of education, and income.

resultsControlling for relevant covariates, Shuar adults reporting the highest level of somatic symptoms (three symptoms) were more likely to exhibit elevated systolic (β = 0.20, p = 0.04) and diastolic blood pressure (β = 0.23, p = 0.03), in comparison to adults reporting no symptoms. Shuar adults reporting two symptoms, compared to no symptoms, were more likely to exhibit elevated EBV antibody concentrations (β = 0.34, p = < 0.01).

conclusionsThese preliminary findings demonstrate that somatic symptoms reported by Shuar men and women are associated with physiological measures widely associated with chronic psychosocial stress. These findings complement the cross-cultural literature in medical anthropology documenting the close connection between the expression of somatic symptoms and stressful life circumstances and highlight the important role that human biologists can play in exploring biocultural phenomena.

Indexed as

Antibodies, ViralHerpesvirus 4, HumanAdolescentAdultAgedBiomarkersBlood PressureEcuadorEpstein-Barr Virus InfectionsFemaleHumansHypertensionIndians, South AmericanMaleMiddle AgedYoung AdultAntibodies, ViralBiomarkersAmazondiastolic blood pressure (DBP)EcuadorEpstein–Barr virus (EBV) antibodiesShuarsomatic symptomsstresssystolic blood pressure (SBP)

Identifiers

PMID39613339
PMCPMC11670149

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.