Evidence map›Paper›PMID 39612462›Full record

ArticleMedicine2024

Effects of Bailing capsules combined with levothyroxine sodium on autoimmune thyroiditis.

Bai-Yu Su, Tao Wu, Li-Shuang Huo, Zhe Qu, Bu-Lang Gao

Abstract read
In one paragraph

Article in Medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Bai-Yu SuDepartment of Endocrinology, Shijiazhuang People's Hospital, Shijiazhuang, China.
Tao WuDepartment of Endocrinology, Shijiazhuang People's Hospital, Shijiazhuang, China.
Li-Shuang HuoDepartment of Endocrinology, Shijiazhuang People's Hospital, Shijiazhuang, China.
Zhe QuDepartment of Neurosurgery, Shijiazhuang People's Hospital, Shijiazhuang, China.
Bu-Lang GaoDepartment of Endocrinology, Shijiazhuang People's Hospital, Shijiazhuang, China.ORCID 0000-0003-4668-0737

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To explore the clinical effects and adverse reactions of Bailing capsules combined with levothyroxine sodium for autoimmune thyroiditis, 70 patients with autoimmune thyroiditis were retrospectively enrolled and divided into the Bailing treatment group and the control, both consisting of 35 patients. The control group was treated with levothyroxine sodium alone, and the treatment group with Bailing capsules combined with levothyroxine sodium. The clinical efficacy, thyroid function indicators, antibodies and inflammatory indicators, and adverse drug reactions were analyzed. The total treatment effective rate was significantly (P = .04) higher in the treatment (94.29%) than in the control group (77.14%). After treatment, the levels of free triiodothyronine (8.69 ± 1.02 vs 6.70 ± 1.12 pmol/L) and free thyroxine (FT4) (20.05 ± 2.33 vs 13.00 ± 2.41 pmol/L) were significantly (P < .001) higher in the treatment group than those in the control group, the levels of thyroid peroxidase antibody (TPOAb) (298.70 ± 65.08 vs 735.15 ± 93.39 U/mL) and thyroglobulin antibodies (TgAb) (93.37 ± 21.10 vs 194.20 ± 37.48 U/mL) in the treatment group were significantly (P < .05) lower than those in the control group, and the interleukin-6 (IL-6) (82.83 ± 3.15 vs 97.17 ± 2.27 ng/L) and interleukin-17 (6.02 ± 0.67 vs 6.89 ± 0.72 ng/L) indicators in the treatment group were significantly (P < .05) lower than those in the control group. No significant (P = .393) difference was found in the adverse drug reaction. In conclusion, Bailing capsules combined with levothyroxine sodium are effective and safe for autoimmune thyroiditis, with good control of disease progression, improvement of thyroid function, reduction of thyroid function-related antibody level, and inhibition of inflammation.

Indexed as

Thyroiditis, AutoimmuneThyroxineAdultAutoantibodiesCapsulesDrugs, Chinese HerbalDrug Therapy, CombinationFemaleHumansMaleMiddle AgedRetrospective StudiesThyroid Function TestsTreatment OutcomeTriiodothyronineAutoantibodiesCapsulesDrugs, Chinese HerbalThyroxineTriiodothyronine

Identifiers

PMID39612462
PMCPMC11608710

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.