Evidence map›Paper›PMID 39612361›Full record

ArticleThe Journal of physiology2024

Rad-mediated inhibition of Ca

Xiang-Qun Hu, Rui Song, Chiranjib Dasgupta, Taiming Liu, Meijuan Zhang, Stephen Twum-Barimah, Arlin B Blood, Lubo Zhang

Abstract read
In one paragraph

Article in The Journal of physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiang-Qun HuLawrence D. Longo, MD Center for Perinatal Biology, Department of Basic Sciences, Loma Linda University School of Medicine, Loma Linda, CA, USA.ORCID 0000-0003-1626-9541
Rui SongLawrence D. Longo, MD Center for Perinatal Biology, Department of Basic Sciences, Loma Linda University School of Medicine, Loma Linda, CA, USA.ORCID 0000-0002-5485-3741
Chiranjib DasguptaLawrence D. Longo, MD Center for Perinatal Biology, Department of Basic Sciences, Loma Linda University School of Medicine, Loma Linda, CA, USA.
Taiming LiuDivision of Neonatology, Department of Pediatrics, Loma Linda University School of Medicine, Loma Linda, CA, USA.
Meijuan ZhangDivision of Neonatology, Department of Pediatrics, Loma Linda University School of Medicine, Loma Linda, CA, USA.
Stephen Twum-BarimahLawrence D. Longo, MD Center for Perinatal Biology, Department of Basic Sciences, Loma Linda University School of Medicine, Loma Linda, CA, USA.
Arlin B BloodLawrence D. Longo, MD Center for Perinatal Biology, Department of Basic Sciences, Loma Linda University School of Medicine, Loma Linda, CA, USA.ORCID 0000-0002-4803-5021
Lubo ZhangLawrence D. Longo, MD Center for Perinatal Biology, Department of Basic Sciences, Loma Linda University School of Medicine, Loma Linda, CA, USA.ORCID 0000-0002-9386-8938

Funding

Uterine Vascular Adaptation to Pregnancy and Chronic HypoxiaP01HD083132 · NICHD · LOMA LINDA UNIVERSITY · PI ZHANG, LUBO · 2016 to 2020
$6.3M
Mechanisms of uterine artery hemodynamics adaptation to pregnancy and gestational hypoxiaR01HL169157 · NHLBI · LOMA LINDA UNIVERSITY · PI Arlin B Blood, Lubo Zhang · 2023 to 2026
$3.2M
Mechanisms of newborn pulmonary hypertension caused by chronic intrauterine hypoxiaR01HL155295 · NHLBI · LOMA LINDA UNIVERSITY · PI BLOOD, ARLIN B, WILSON, SEAN M · 2022 to 2025
$3.1M
Gestational Hypoxia and Programming of Maternal, Fetal and Newborn Vascular FunctionR01HL149608 · NHLBI · LOMA LINDA UNIVERSITY · PI PEARCE, WILLIAM J., WILSON, SEAN M · 2020 to 2023
$3.1M
HHS | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) HD083132HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) HL149608HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) HL155295HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) HL169157NHLBI NIH HHS R01 HL149608NHLBI NIH HHS R01 HL155295NHLBI NIH HHS R01 HL169157NICHD NIH HHS P01 HD083132
6 · The paper itself

Abstract

The striking increase of uterine blood flow during pregnancy is essential for normal fetal development as well as for cardiovascular well-being of the mother. Yet, the underlying mechanisms of pregnancy-mediated vasodilatation of the uterine artery are not fully understood. In this study, we test the hypothesis that Rad, a monomeric G protein, is a novel regulatory mechanism in inhibiting Ca

Indexed as

Adaptation, PhysiologicalCalcium Channels, L-TypeHemodynamicsUterine ArteryAnimalsFemaleMuscle, Smooth, VascularMyocytes, Smooth MusclePregnancySheepVascular ResistanceVasoconstrictionVasodilationCalcium Channels, L-TypeL-type calcium channel alpha(1C)CaV1.2 channelpregnancyRaduterine blood flowuterine vascular resistance

Identifiers

PMID39612361
PMCPMC11652214

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.