Evidence map›Paper›PMID 39612086›Full record

Trial reportJournal of cancer survivorship : research and practice2026

Symptom management interventions influence unscheduled health services use among cancer survivors and caregivers.

Terry Badger, Chris Segrin, Tracy E Crane, Pavani Chalasani, Waqas Arslan, Mary Hadeed, Nathan Cunicelli, Charles W Given, Alla Sikorskii

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of cancer survivorship : research and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Terry BadgerAdvanced Nursing Practice and Science Division, University of Arizona College of Nursing, Tucson, AZ, USA. tbadger@arizona.edu.
Chris SegrinDepartment of Communications, University of Arizona, Tucson, AZ, USA.
Tracy E CraneUniversity of Miami Miller School of Medicine, Miami, FL, USA.
Pavani ChalasaniDivision of Hematology-Oncology, George Washington University, Washington, DC, USA.
Waqas ArslanCollege of Medicine, University of Arizona, Phoenix, AZ, USA.
Mary HadeedAdvanced Nursing Practice and Science Division, University of Arizona College of Nursing, Tucson, AZ, USA.
Nathan CunicelliAdvanced Nursing Practice and Science Division, University of Arizona College of Nursing, Tucson, AZ, USA.
Charles W GivenMichigan State University College of Nursing, East Lansing, MI, USA.
Alla SikorskiiDepartment of Psychiatry, Michigan State University College of Osteopathic Medicine, East Lansing, MI, USA.

Funding

VITAMIN AP30CA023074 · NCI · UNIVERSITY OF ARIZONA · PI Dan Theodorescu · 1985 to 2026
$110.2M
Improving Informal Caregivers' and Cancer Survivors' Psychological Distress, Symptom Management and Health Care UseR01CA224282 · NCI · UNIVERSITY OF ARIZONA · PI BADGER, TERRY A · 2018 to 2021
$2.7M
NCI NIH HHS P30 CA023074NCI NIH HHS R01 CA224282
6 · The paper itself

Abstract

purposeThree sequences of telephone symptom management interventions were tested on use of unscheduled health services among cancer survivors with depressive or anxiety symptoms during treatment (N = 334) and their informal caregivers (N = 333).

methodsThe three 12-week intervention sequences were as follows: (1) Symptom Management and Survivorship Handbook (SMSH), (2) a combined 8-week SMSH + Telephone Interpersonal Counseling (TIPC) followed by SMSH for 4 weeks, and (3) SMSH for 4 weeks followed by a combined SMSH + TIPC if no response to SMSH alone. Survivor-caregiver dyads were first randomized to SMSH or a combined SMSH + TIPC. If the survivor's depressive or anxiety symptoms persisted after 4 weeks of SMSH alone, the dyad was randomized the second time to continue with SMSH alone or TIPC was added to SMSH. All participants were assessed at baseline and 13 and 17 weeks. Health service use was compared between randomized groups and among the three sequences.

resultsSurvivors were 60.2 years of age, 79% were female, and 41% were Hispanic. Caregivers were 54.8 years of age; 67% were female. The significantly lower rate of emergency department (ED) or urgent care visits for survivors was found in the SMSH + TIPC intervention sequence compared to the SMSH alone in the second randomization and for the third intervention sequence compared to the first.

conclusionsAdding TIPC to SMSH after week 4 when survivors experienced persisting depressive or anxiety symptoms reduced ED/urgent care visits compared to SMSH alone. IMPLICATIONS FOR CANCER SURVIVORS: Managing depression and anxiety symptoms may help prevent ED/urgent care visits and worsening of other symptoms.

Indexed as

Cancer SurvivorsCaregiversNeoplasmsPatient Acceptance of Health CareAdultAgedAnxietyDepressionFemaleHumansMaleMiddle AgedTelephoneAnxietyCancer survivors and caregiversCancer survivorshipDepressive symptomsSymptom managementUnscheduled health services use

Identifiers

PMID39612086
PMCPMC12151082

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.