Evidence map›Paper›PMID 39611983›Full record

ArticleCurrent microbiology2024

Closely Related Brucella Species Widely Differ in their Vegetative and Intracellular Growth.

Nazarena Wade, Diego J Comerci, Alfonso Soler-Bistué, María Inés Marchesini

Abstract read
PubMed Publisher
In one paragraph

Article in Current microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nazarena WadeLaboratorio de Genómica Experimental Bacteriana, Instituto de Investigaciones Biotecnológicas, Escuela de Bio y Nanotecnologías (EByN), Universidad Nacional de San Martín (UNSAM), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Campus Miguelete, Av. 25 de mayo y Francia CP (1650), San Martín, Buenos Aires, Argentina.
Diego J ComerciLaboratorio de Genómica Experimental Bacteriana, Instituto de Investigaciones Biotecnológicas, Escuela de Bio y Nanotecnologías (EByN), Universidad Nacional de San Martín (UNSAM), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Campus Miguelete, Av. 25 de mayo y Francia CP (1650), San Martín, Buenos Aires, Argentina.ORCID http://orcid.org/0000-0003-1949-4226
Alfonso Soler-BistuéLaboratorio de Genómica Experimental Bacteriana, Instituto de Investigaciones Biotecnológicas, Escuela de Bio y Nanotecnologías (EByN), Universidad Nacional de San Martín (UNSAM), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Campus Miguelete, Av. 25 de mayo y Francia CP (1650), San Martín, Buenos Aires, Argentina. asoler@iib.unsam.edu.ar.ORCID http://orcid.org/0000-0002-3917-0002
María Inés MarchesiniLaboratorio de Genómica Experimental Bacteriana, Instituto de Investigaciones Biotecnológicas, Escuela de Bio y Nanotecnologías (EByN), Universidad Nacional de San Martín (UNSAM), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Campus Miguelete, Av. 25 de mayo y Francia CP (1650), San Martín, Buenos Aires, Argentina. imarchesini@iib.unsam.edu.ar.ORCID http://orcid.org/0000-0002-8540-2337

Funding

Agencia Nacional de Promoción de la Investigación, el Desarrollo Tecnológico y la Innovación PICT-2019-02535Agencia Nacional de Promoción de la Investigación, el Desarrollo Tecnológico y la Innovación PICT-2020-0521Agencia Nacional de Promoción de la Investigación, el Desarrollo Tecnológico y la Innovación PICT-2021-Cat-0154Consejo Nacional de Investigaciones Científicas y Técnicas 2022-2024 (PIP)Fondo para la Investigación Científica y Tecnológica PICT-2017-0424Fondo para la Investigación Científica y Tecnológica PICT-2018-0476International Center for Genetic Engineering and Biotechnology CRP/ARG18-06_EC
6 · The paper itself

Abstract

Growth rate is a key prokaryotic trait that allows for estimating fitness and understanding cell metabolism. While it has been well studied in model organisms, there is limited data on slow-growing bacteria. In particular, there is a lack of quantitative studies on Brucella species. This genus includes important microorganisms that are causative agents of brucellosis, one of the most widespread bacterial zoonoses, affecting several species of animals, including humans. Brucella species exhibit approximately 97% genomic similarity. Despite this, Brucella species show different host preferences, zoonotic risks, and pathogenicity. After more than one hundred years of research, numerous aspects of Brucella biology, such as in vivo and in vitro growth, remain poorly characterized. In this work, we analyzed vegetative and intracellular growth of the classical Brucella species (B. abortus, B. melitensis, B. suis, B. ovis, and B. canis). Strikingly, each species displayed distinct growth parameters in culture. Doubling time (DT) ranged from 2.7 hs

Indexed as

BrucellaBrucellosisAnimalsCell LineGenome, BacterialHumansMacrophagesMiceSpecies Specificity

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.