Evidence map›Paper›PMID 39611943›Full record

ArticleEuropean journal of applied physiology2025

Boys vs men differences in muscular fatigue, muscle and cerebral oxygenation during maximal effort isometric contractions: the effect of muscle blood flow restriction.

Leonidas Kastritseas, Aggelos Koutlas, Anastasios Kounoupis, Stella Kritikou, Stavros Papadopoulos, Ilias Smilios, Konstantina Dipla, Andreas Zafeiridis

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Article in European journal of applied physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Leonidas KastritseasLaboratory of Exercise Physiology and Biochemistry, Department of Physical Education and Sports Science at Serres, Aristotle University of Thessaloniki, Ag. Ioannis, 62100, Serres, Greece.
Aggelos KoutlasLaboratory of Exercise Physiology and Biochemistry, Department of Physical Education and Sports Science at Serres, Aristotle University of Thessaloniki, Ag. Ioannis, 62100, Serres, Greece.
Anastasios KounoupisLaboratory of Exercise Physiology and Biochemistry, Department of Physical Education and Sports Science at Serres, Aristotle University of Thessaloniki, Ag. Ioannis, 62100, Serres, Greece.
Stella KritikouLaboratory of Exercise Physiology and Biochemistry, Department of Physical Education and Sports Science at Serres, Aristotle University of Thessaloniki, Ag. Ioannis, 62100, Serres, Greece.
Stavros PapadopoulosLaboratory of Exercise Physiology and Biochemistry, Department of Physical Education and Sports Science at Serres, Aristotle University of Thessaloniki, Ag. Ioannis, 62100, Serres, Greece.
Ilias SmiliosDepartment of Physical Education and Sport Science, Democritus University of Thrace, 69100, Komotini, Greece.
Konstantina DiplaLaboratory of Exercise Physiology and Biochemistry, Department of Physical Education and Sports Science at Serres, Aristotle University of Thessaloniki, Ag. Ioannis, 62100, Serres, Greece.
Andreas ZafeiridisLaboratory of Exercise Physiology and Biochemistry, Department of Physical Education and Sports Science at Serres, Aristotle University of Thessaloniki, Ag. Ioannis, 62100, Serres, Greece. zafeirid@phed-sr.auth.gr.ORCID http://orcid.org/0000-0002-0435-6659

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo examine whether the children's superiority, over adults, to resist fatigue during repeated maximal-efforts depends on their often-cited oxidative advantage, attributed to greater muscle blood flow and O

methodsEleven men (23.3 ± 1.8yrs) and eleven boys (11.6 ± 1.1 yrs) performed 15 maximal-effort handgrips (3-s contraction/3-s rest) under two conditions: free-flow circulation (FF) and arterial-occlusion (OCC). Force, muscle-oxygenation (TSImuscle) and cerebral-oxygenation (oxyhemoglobin-O

resultsIn boys, force declined less (- 26.3 ± 2.6 vs. - 34.4 ± 2.4%) and at slower rate (- 1.56 ± 0.16 vs. - 2.24 ± 0.17%·rep

conclusionDuring repeated maximal-efforts: (i) blood flow is a significant contributor to children's superiority over adults to resist fatigue; (ii) age-difference in muscle hypoxia/deoxygenation is rather attributed to men's greater metabolic demand than to lower muscle-perfusion; and (iii) cerebral oxygenation/blood volume increase more in men than boys under free circulation, implying greater brain activation.

Indexed as

BrainIsometric ContractionMuscle FatigueMuscle, SkeletalOxygenOxygen ConsumptionAdultCerebrovascular CirculationChildHand StrengthHumansMaleRegional Blood FlowYoung AdultOxygenBlood flowBoysCerebral oxygenationChildrenExerciseFatigueIschemiaIsometric exerciseMuscle oxygenationNear infrared spectroscopy

Identifiers

PMID39611943

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.