ArticleJournal of applied clinical medical physics2025
Automated hippocampal sparing whole brain radiotherapy with simultaneous integrated boost for multiple brain metastases: Halcyon, HyperArc on TrueBeam, and coplanar TrueBeam.
Article in Journal of applied clinical medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Automated hippocampal sparing whole brain radiotherapy with simultaneous integrated boost for multiple brain metastases: Halcyon, HyperArc on TrueBeam, and coplanar TrueBeam.Journal of applied clinical medical physics · 2025Article
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5 authors.
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Abstract
purposeTo demonstrate the ease and feasibility that hippocampal sparing whole brain (WB) simultaneous integrated boost (HSWB-SIB) plans can be generated using knowledge-based planning and Eclipse Scripting Application Programming Interface (ESAPI) for three different modalities, HyperArc on TrueBeam (TB-HA), a coplanar beam arrangement on TrueBeam (TB-Co), and the ring-mounted Halcyon LINAC (Hal).
methodsTwelve patients with 2-14 brain metastases were retrospectively replanned for HSWB-SIB using a published HSWB RapidPlan model with modifications for the automated addition of SIB to metastases. Prescribed dose was 30 Gy to the WB planning target volume (PTV) and 50 Gy to the metastases in 10 fractions. Eclipse treatment planning system (v16.1) was used with a 6 MV-FFF beam and Acuros XB dose algorithm.
resultsThe methodology was successfully used for all modalities, generating plans in under 30 min. The plan doses were normalized to the WB PTV D
conclusionThe novel modification of the preexisting HSWB RapidPlan model with the automated inclusion of SIB objectives allows for easy, intuitive planning of complex HSWB-SIB treatments. All modalities demonstrated can be used with clinically comparable results. Other institutions are recommended to pursue and validate this HSWB-SIB technique to increase the accessibility of a single-course of high-quality treatment for patients with multiple brain lesions.
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