Evidence map›Paper›PMID 39611839›Full record

ArticlemBio2025

Development and utilization of

Kristina N Delgado, Crystal F Vicente, Christopher M Hennelly, Farhang Aghakhanian, Jonathan B Parr, Kevin P Claffey, Justin D Radolf, Kelly L Hawley, Melissa J Caimano

Abstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Formal description ofInternational journal of systematic and evolutionary microbiology · 2026
    Article
  5. Human placental trophoblasts support sustainedbioRxiv : the preprint server for biology · 2026
    Article
  6. TheJornal brasileiro de doencas sexualmente transmissiveis : DST · 2026
    Article
  7. Frontiers in immunology · 2026
    Review
  8. Article
  9. Review
  10. Article
  11. Establishment of the Nichols strain as the type strain ofInternational journal of systematic and evolutionary microbiology · 2025
    Review
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Kristina N DelgadoDepartment of Medicine, University of Connecticut Health, Farmington, Connecticut, USA.ORCID 0000-0003-1170-4102
Crystal F VicenteDepartment of Pediatrics, University of Connecticut Health, Farmington, Connecticut, USA.
Christopher M HennellyInstitute for Global Health and Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Farhang AghakhanianInstitute for Global Health and Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Jonathan B ParrInstitute for Global Health and Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Kevin P ClaffeyDepartment of Cell Biology, University of Connecticut Health, Farmington, Connecticut, USA.
Justin D RadolfDepartment of Medicine, University of Connecticut Health, Farmington, Connecticut, USA.
Kelly L HawleyDepartment of Medicine, University of Connecticut Health, Farmington, Connecticut, USA.ORCID 0000-0001-8587-1662
Melissa J CaimanoDepartment of Medicine, University of Connecticut Health, Farmington, Connecticut, USA.ORCID 0000-0003-1170-4102

Funding

Prevalence of syphilis and other sexually transmitted infections in men and transgender women who have sex with men in Cali, ColombiaU19AI144177 · NIAID · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI MOODY, MICHAEL ANTHONY, RADOLF, JUSTIN D · 2019 to 2023
$11.2M
A Global Syphilis Vaccine Targeting Outer Membrane Proteins of Treponema pallidumU01AI182179 · NIAID · DUKE UNIVERSITY · PI Michael Anthony Moody, Justin D Radolf · 2024 to 2026
$6.9M
INFECTIOUS DISEASE PATHOGENESIS TRAININGT32AI007151 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JULIANO, JONATHAN J · 1985 to 2024
$5.5M
Connecticut Children's Medical Center (Connecticut Children's) N/AHHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) Diversity Supplement U19 AI144177NIAID NIH HHS T32 AI007151NIAID NIH HHS U01 AI182179NIAID NIH HHS U19 AI144177Open Philantropy/Good Ventures N/A
6 · The paper itself

Abstract

Syphilis is a sexually transmitted infection caused by the highly invasive and immunoevasive spirochetal pathogen IMPORTANCE: Syphilis, a sexually transmitted infection caused by

Indexed as

Green Fluorescent ProteinsSyphilisTreponema pallidumAnimalsAntibodies, BacterialDisease Models, AnimalHost-Pathogen InteractionsHumansMacrophagesMaleMiceRabbitsTestisTreponemaAntibodies, BacterialGreen Fluorescent Proteinsbactericidal antibodiesBamAbone marrow-derived murine macrophagesflow cytometryGFPopsonophagocytosisspirochetessyphilisTreponema pallidum

Identifiers

PMID39611839
PMCPMC11708019

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.