ArticleJournal of applied clinical medical physics2025
Clinical use of Gafchromic EBT4 film for in vivo dosimetry for total body irradiation.
Article in Journal of applied clinical medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The trial behind it
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Who cites it
5 citing papers in PubMed.
- Clinical in-vivo dosimetry for total skin electron therapy using gafchromic™ EBT4 film.Journal of applied clinical medical physics · 2026Article
- Benchmarking a new radiochromic film type for photon and proton beam dosimetry.Physics and imaging in radiation oncology · 2026Article
- Commissioning of a near real-time in vivo film dosimetry system.Journal of applied clinical medical physics · 2026Article
- Activity-dependent transit dose assessment inPrecision radiation oncology · 2025Article
- Clinical use of Gafchromic EBT4 film for in vivo dosimetry for total body irradiation.Journal of applied clinical medical physics · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
purposeIn vivo dosimetry is a common requirement to validate dose accuracy/uniformity in total body irradiation (TBI). Several detectors can be used for in vivo dosimetry, including thermoluminescent dosimeters (TLDs), diodes, ion chambers, optically stimulated luminescent dosimeters (OSLDs), and film. TLDs are well established for use in vivo but required expertise and clinical system availability may make them impractical for multifractionated TBI. OSLDs offer quick readout, but recalls have restricted their use. The purpose of this work was to validate the newly available Gafchromic EBT4 film for TBI in vivo dosimetry.
methodsFilm calibration curves were created under standard conditions (6MV/15MV, 1.5/3.0 cm depth, 100 cm source-to-surface distance (SSD), 10 × 10 cm
resultsThe shortest development time that resulted in accurate dosimetry and allowed for adequate physician review time was 4 h (± 4% dose accuracy). Film entrance and exit dose measurements were within ± 3.8% of ion chamber and diode readings for 6MV and 15MV beams. Patient film measurements were within ∼ ± 5% for the majority of anatomical measurement locations; however, film and OSLD readings for some anatomic locations deviated by > 10%.
conclusionsThese results indicate that EBT4 film can be utilized for accurate in vivo dosimetry for TBI patients and shows good agreement with diode and ion chamber measurements. Further investigation into film and OSLD differences was not possible due to OSLD recalls.
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