ArticleJournal of applied clinical medical physics2025
Enhancing targeted doses: Low-energy photon lipiodol-enhanced radiotherapy (LEPERT) for liver cancer patients.
Article in Journal of applied clinical medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- From Marker to Modulator: Lipiodol-Mediated Dose Enhancement in Liver Tumor Radiotherapy.Cardiovascular and interventional radiology · 2026Article
- Lipiodol-Mediated Dose Enhancement in Radiation Therapy: A Phantom and In Vitro Study in Hepatocellular Carcinoma.Cardiovascular and interventional radiology · 2026Article
- Heterogeneity of the liver cancer tumor microenvironment: mitochondrial metabolism and causal inference through Mendelian randomization.Discover oncology · 2025Article
- Enhancing targeted doses: Low-energy photon lipiodol-enhanced radiotherapy (LEPERT) for liver cancer patients.Journal of applied clinical medical physics · 2025Article
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1 author.
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Abstract
objectivesThis study proposes a novel approach, "Low-energy photon Lipiodol-Enhanced Radiotherapy" (LEPERT), for patients with liver cancer. Moreover, we evaluate the dose difference of the conventional treatment planning with 10 MV X-ray beam (MV-plan) and LEPERT.
methodsThe computed tomography (CT) was modeled with the Monte Carlo simulation. For LEPERT, 120 kV X-ray beams collimated with CT were irradiated on a virtual tumor filled with Lipiodol at 10-50 mg/mL, which was inserted into a whole-body phantom. A prescribed dose of 40 Gy/4fr was irradiated to achieve D
resultsDifferences in the effective energy and off-axis ratio between the measurements and simulations were within 2 keV and 3%, respectively. The D
conclusionThe LEPERT can selectively enhanced only the tumor region with sparing the OAR dose. It could be a novel and effective treatment technique in the point that the treatment machine is a general CT device.
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