Evidence map›Paper›PMID 39611733›Full record

ArticleJournal of applied clinical medical physics2025

A predictive model for Gamma Knife intermediate dose spill: R50%

Ivan L Cordrey, Sare Kucuk, Chester Ramsey, Joseph Bowling, Dharmin D Desai

Abstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. A predictive model for Gamma Knife intermediate dose spill: R50%Journal of applied clinical medical physics · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ivan L CordreyThompson Cancer Survival Center, Cumberland Medical Center, Crossville, Tennessee, USA.
Sare KucukDepartment of Nuclear Engineering Complex, University of Tennessee, Knoxville, Tennessee, USA.
Chester RamseyThompson Cancer Survival Center, Knoxville, Tennessee, USA.
Joseph BowlingThompson Cancer Survival Center, Knoxville, Tennessee, USA.
Dharmin D DesaiAdvanced Oncology Solutions, Varian Medical Systems, Hixson, Tennessee, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMinimizing intermediate dose spill in stereotactic radiosurgery (SRS) for brain treatment is crucial. Intermediate dose spill correlates with the exposure of normal brain tissue to high doses, which increases the risk of radionecrosis. R50%, defined as the volume of the 50% of prescription isodose cloud/planning target volume, is one metric for intermediate dose spill. A predictive model for R50% in linear accelerator VMAT-delivered SRS has been developed Desai et al. (2020) and is called R50%

methodsPhantom calculations were performed on 11 spherical target volumes ranging from 0.001  to 44 cm

resultsThe predicted R50%

conclusionThe R50%

Indexed as

Brain NeoplasmsOrgans at RiskPhantoms, ImagingRadiosurgeryRadiotherapy Planning, Computer-AssistedHumansRadiotherapy DosageRadiotherapy, Intensity-ModulatedGamma KnifeR50%AnalyticSRSsurface areaΔr

Identifiers

PMID39611733
PMCPMC11799916

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.