Evidence map›Paper›PMID 39611592›Full record

ReviewEssays in biochemistry2024

A roadmap of isolating and investigating bacteriophage infecting human gut anaerobes.

Cong Liu, Bo Xing, Zhuoran Li, Junhua Li, Minfeng Xiao

Abstract readReview
In one paragraph

Review in Essays in biochemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. The new age of the phage.Essays in biochemistry · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Cong LiuBGI Research, Shenzhen 518083, China.ORCID 0009-0003-3582-9898
Bo XingBGI Research, Shenzhen 518083, China.
Zhuoran LiBGI Research, Shenzhen 518083, China.
Junhua LiBGI Research, Belgrade 11000, Serbia.
Minfeng XiaoBGI Research, Shenzhen 518083, China.ORCID 0000-0002-0507-7352

Funding

National Natural Science Foundation of China (NSFC) 82250901
6 · The paper itself

Abstract

Bacteriophages, viruses that infect bacteria, play a crucial role in manipulating the gut microbiome, with implications for human health and disease. Despite the vast amount of data available on the human gut virome, the number of cultured phages that infect human gut bacteria-particularly obligate anaerobes-remains strikingly limited. Here, we summarize the resources and basic characteristics of phages that infect the human gut obligate anaerobe. We review various methods for isolating these phages and suggest a strategy for their isolation. Additionally, we outline their impact on the field of viral biology, their interactions with bacteria and humans, and their potential for disease intervention. Finally, we discuss the value and prospects of research on these phages, providing a comprehensive 'Roadmap' that sheds light on the 'dark matter' of phages that infect human gut obligate anaerobes.

Indexed as

BacteriophagesGastrointestinal MicrobiomeBacteria, AnaerobicHumansbacteriophageshuman gut bacteriaisolationobligate anaerobes

Identifiers

PMID39611592
PMCPMC11652169

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.