Evidence map›Paper›PMID 39611435›Full record

ArticleBJU international2025

Association of bi-parametric MRI measures with continence after robot-assisted radical prostatectomy.

Alexander B Nolsøe, Vibeke Løgager, Lars Boesen, Peter Busch Østergren, Henrik Jakobsen, Christian Fuglesang S Jensen, Niels Henrik Bruun, Jens Sønksen, Mikkel Fode

Abstract read
In one paragraph

Article in BJU international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alexander B NolsøeDepartment of Urology, Copenhagen University Hospital, Herlev and Gentofte Hospital, Herlev, Denmark.ORCID https://orcid.org/0000-0001-6493-1961
Vibeke LøgagerDepartment of Urology, Copenhagen University Hospital, Herlev and Gentofte Hospital, Herlev, Denmark.
Lars BoesenDepartment of Urology, Copenhagen University Hospital, Herlev and Gentofte Hospital, Herlev, Denmark.ORCID https://orcid.org/0000-0003-2414-962X
Peter Busch ØstergrenDepartment of Urology, Copenhagen University Hospital, Herlev and Gentofte Hospital, Herlev, Denmark.ORCID https://orcid.org/0000-0003-4762-039X
Henrik JakobsenDepartment of Urology, Copenhagen University Hospital, Herlev and Gentofte Hospital, Herlev, Denmark.ORCID https://orcid.org/0000-0002-4753-8807
Christian Fuglesang S JensenDepartment of Urology, Copenhagen University Hospital, Herlev and Gentofte Hospital, Herlev, Denmark.
Niels Henrik BruunAalborg University Hospital, Aalborg, Denmark.
Jens SønksenDepartment of Urology, Copenhagen University Hospital, Herlev and Gentofte Hospital, Herlev, Denmark.
Mikkel FodeDepartment of Urology, Copenhagen University Hospital, Herlev and Gentofte Hospital, Herlev, Denmark.ORCID https://orcid.org/0000-0002-8963-4581

Funding

Aage og Johanne Louis-Hansens FondChristian Larsen & Dommer Ellen Larsens LegatDagmar Marshalls FondThe Capital Region of Denmark's health strategy for the focus area "Increased capacity for more minimally invasive surgical treatment"
6 · The paper itself

Abstract

objectiveTo investigate the association between pre- and postoperative magnetic resonance imaging (MRI) measurements of the membranous urethra and the prostate volume and continence following robot-assisted radical prostatectomy (RARP). PATIENTS AND

methodsFrom December 2018 to June 2022, 100 continent patients undergoing unilateral nerve-sparing or non-nerve-sparing RARP were included in this cohort study. Bi-parametric MRI scans were performed before and 12 months after RARP and measurements included the membranous urethral length (MUL) measured in cm (mMUL) and in the number of image slices (sMUL; 3 mm/slice), the membranous urethral diameter (MUD), and the prostate volume. Urinary function was evaluated by the International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form (ICIQ-UI SF) and continence, defined as the use of zero pads and the answer 'never' to the ICIQ-UI SF question regarding incontinence frequency or <8 g urine-loss per 24 h. Regression with robust variance estimates was used to analyse the association between measurements and outcomes.

resultsAt 12 months, continence and MRI data were available for 82 patients. The continence rate was 63% and the median (interquartile range) ICIQ-UI SF score was 4 (0-9). Both preoperative MUL measurements were associated with continence at 12 months. Every extra 5 mm of MUL increased the likelihood of being continent by 13 percentage points (P = 0.03) and every additional slice of sMUL increased it by 6 percentage points (P = 0.05). Both postoperative MUL measurements were associated with better continence and lower ICIQ-UI SF scores (P < 0.01). A larger prostate volume was associated with urinary incontinence at 12 months, with a small effect size. The MUD was not associated with continence.

conclusionPreoperative mMUL and sMUL are associated with continence at 12 months after RARP. The sMUL may be a useful measurement when only the axial plane is available, and the slice gap is known. Postoperative MUL measurements are strongly associated with continence, while MUD and prostate volume hold minimal prognostic value.

Indexed as

Magnetic Resonance ImagingPostoperative ComplicationsProstatectomyProstatic NeoplasmsRobotic Surgical ProceduresUrethraUrinary IncontinenceAgedHumansMaleMiddle AgedProstatemagnetic resonance imagingmembranous urethral lengthprostate cancerrobot‐assisted radical prostatectomyurinary incontinence

Identifiers

PMID39611435
PMCPMC11913601

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.