Evidence map›Paper›PMID 39611395›Full record

ArticleJournal of extracellular vesicles2024

Monocyte-derived extracellular vesicles, stimulated by Trypanosoma cruzi, enhance cellular invasion in vitro via activated TGF-β1.

Ephraim A Ansa-Addo, Paras Pathak, Maria V McCrossan, Izadora Volpato Rossi, Mahamed Abdullahi, Dan Stratton, Sigrun Lange, Marcel I Ramirez, Jameel M Inal

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of extracellular vesicles, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Towards a map of the immune system manipulation network byFrontiers in cellular and infection microbiology · 2025
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ephraim A Ansa-AddoSchool of Human Sciences, Cell Communication in Disease Pathology, London Metropolitan University, London, UK.
Paras PathakSchool of Human Sciences, Cell Communication in Disease Pathology, London Metropolitan University, London, UK.
Maria V McCrossanImmunology Unit, London School of Hygiene and Tropical Medicine, London, UK.
Izadora Volpato RossiSchool of Human Sciences, Cell Communication in Disease Pathology, London Metropolitan University, London, UK.
Mahamed AbdullahiSchool of Human Sciences, Cell Communication in Disease Pathology, London Metropolitan University, London, UK.
Dan StrattonSchool of Life, Health & Chemical Sciences, The Open University, Milton Keynes, UK.
Sigrun LangeTissue Architecture and Regeneration Research Group, School of Life Sciences, University of Westminster, London, UK.
Marcel I RamirezCarlos Chagas Institute, Fundacao Oswaldo Cruz, (FIOCRUZ-PR), Curitiba, Brazil.
Jameel M InalSchool of Human Sciences, Cell Communication in Disease Pathology, London Metropolitan University, London, UK.ORCID 0000-0002-7200-0363

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior PrintEuropean Commission IAPP 612224London Metropolitan University Quality-Related ResearchRoyal Society IV0871706/ LMU
6 · The paper itself

Abstract

During cell invasion, large Extracellular Vesicle (lEV) release from host cells was dose-dependently triggered by Trypanosoma cruzi metacyclic trypomastigotes (Mtr). This lEV release was inhibited when IP

Indexed as

CalciumExtracellular VesiclesMonocytesTransforming Growth Factor beta1Trypanosoma cruziChagas DiseaseHumansMembrane MicrodomainsCalciumTGFB1 protein, humanTransforming Growth Factor beta1cell uptakeendocytosisextracellular vesiclesTrypanosoma cruzi

Identifiers

PMID39611395
PMCPMC11605483

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.