Evidence map›Paper›PMID 39611318›Full record

ReviewFEMS yeast research2024

Diacylglycerol metabolism and homeostasis in fungal physiology.

Sudipta Mondal, Biswajit Pal, Rajan Sankaranarayanan

Abstract readReview
In one paragraph

Review in FEMS yeast research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Metabolomic Profiling ofJournal of fungi (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sudipta MondalCSIR - Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad 50007, India.
Biswajit PalCSIR - Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad 50007, India.
Rajan SankaranarayananCSIR - Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad 50007, India.ORCID 0000-0003-4524-9953

Funding

FIRST MLP-0162NCP MLP-0138
6 · The paper itself

Abstract

Diacylglycerol (DAG) is a relatively simple and primitive form of lipid, which does not possess a phospholipid headgroup. Being a central metabolite of the lipid metabolism network, DAGs are omnipresent in all life forms. While the role of DAG has been established in membrane and storage lipid biogenesis, it can impart crucial physiological functions including membrane shapeshifting, regulation of membrane protein activity, and transduction of cellular signalling as a lipid-based secondary messenger. Besides, the chemical diversity of DAGs, due to fatty acyl chain composition, has been proposed to be the basis of its functional diversity. Therefore, cells must regulate DAG level at a spatio-temporal scale for homeostasis and adaptation. The vast network of eukaryotic lipid metabolism has been unravelled majorly by studying yeast models. Here, we review the current understanding and the emerging concepts in metabolic and functional aspects of DAG regulation in yeast. The implications can be extended to understand pathogenic fungi and mammalian counterparts as well as disease aetiology.

Indexed as

DiglyceridesHomeostasisFungiLipid MetabolismSaccharomyces cerevisiaeSignal TransductionDiglyceridesacyl-chain diversitydiacylglyceroldisco-interacting protein 2lipid metabolismlipid second messengermembrane contact siteorganelle membranes

Identifiers

PMID39611318
PMCPMC11631473

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.