Evidence map›Paper›PMID 39611099›Full record

Trial reportPathology oncology research : POR2024

Impact of limb ischemic preconditioning on the incidence of vein thrombosis in patients with peripherally inserted central catheter.

Han Zhao, Changhua Kou, Hao Zhao, Qing Liu, Maosheng He, Cong Wang, Saisai Zhu, Li Ma, Yun Wang

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Pathology oncology research : POR, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Han Zhao *Clinic for Kidney and Hypertensive Diseases, Hanover Medical School, Hanover, Germany.
Changhua Kou *Department of Hepatobiliary Pancreatic Center, Xuzhou City Central Hospital, The Xuzhou School of Clinical Medicine of Nanjing Medical University, The Affiliated Hospital of the Southeast University Medical School, Xuzhou, Jiangsu, China.
Hao ZhaoDepartment of Vascular Surgery, Xuzhou City Central Hospital, The Affiliated Hospital of the Southeast University Medical School, Xuzhou, Jiangsu, China.
Qing LiuDepartment of Gynecology Department, Xuzhou City Central Hospital, The Xuzhou School of Clinical Medicine of Nanjing Medical University, The Affiliated Hospital of the Southeast University Medical School, Xuzhou, Jiangsu, China.
Maosheng HeDepartment of Color Ultrasound Department, Xuzhou City Central Hospital, The Xuzhou School of Clinical Medicine of Nanjing Medical University, The Affiliated Hospital of the Southeast University Medical School, Xuzhou, Jiangsu, China.
Cong WangDepartment of Hepatobiliary Pancreatic Center, Xuzhou City Central Hospital, The Xuzhou School of Clinical Medicine of Nanjing Medical University, The Affiliated Hospital of the Southeast University Medical School, Xuzhou, Jiangsu, China.
Saisai ZhuDepartment of Hepatobiliary Pancreatic Center, Xuzhou City Central Hospital, The Xuzhou School of Clinical Medicine of Nanjing Medical University, The Affiliated Hospital of the Southeast University Medical School, Xuzhou, Jiangsu, China.
Li Ma *Department of Thyroid and Breast Surgery, Xuzhou City Central Hospital, The Affiliated Hospital of the Southeast University Medical School, Xuzhou, Jiangsu, China.
Yun Wang *Department of Hepatobiliary Pancreatic Center, Xuzhou City Central Hospital, The Xuzhou School of Clinical Medicine of Nanjing Medical University, The Affiliated Hospital of the Southeast University Medical School, Xuzhou, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Peripherally inserted central catheters (PICC) are increasingly used in clinical practice, which also leads to an increased incidence of PICC-related thrombosis. Local thrombus formation could be prevented by limb ischemic preconditioning (IPC). This study aimed to determine whether IPC can prevent deep vein thrombosis in patients with PICC. Methods: A total of 600 breast cancer patients receiving PICC were randomized into two groups between July 2016 and July 2018 at the Department of Radiation Oncology. In the preconditioning group, 5 min of ischemic preconditioning was performed three times before PICC, whereas no preconditioning was performed in the sham group. The coagulation function levels, the PICC-related complications, the length of hospital stay, the cost of hospitalization, and the satisfaction of patients were compared. Results: The coagulation function levels of patients in the preconditioning group were more normal than in patients from the sham group. In total, 56/300 patients in the sham group had presence of PICC-related thrombosis, with only 23/300 in the IPC group, with no significant difference in other complications between the two groups. However, a longer hospital stay was observed in the sham group compared to the IPC group. Moreover, the cost of hospitalization was also reduced in the IPC group, which also improved the satisfaction of patients. Conclusion: Limb ischemic preconditioning may attenuate the severity of vein thrombosis in patients with PICC, which contributes to reducing the incidence of PICC-related thrombosis in clinical practice.

Indexed as

Catheterization, PeripheralIschemic PreconditioningVenous ThrombosisAdultAgedBreast NeoplasmsCatheterization, Central VenousExtremitiesFemaleHumansIncidenceLength of StayMiddle Agedlimb ischemic preconditioningperipherally inserted central catheterPICC-related complicationstumorvein thrombosis

Identifiers

PMID39611099
PMCPMC11602314

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.