Evidence map›Paper›PMID 39611078›Full record

ArticleFrontiers in physiology2024

Impact of co-administration of apricot kernels and caffeine on adult male diabetic albino rats.

Ahmed El Sayed Nour El-Deen, Ahmad Mohamad Taha, Almoatazbellah Elsayed, Ahmed Noaman Ali, Reda Samir Taha

Abstract read
In one paragraph

Article in Frontiers in physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ahmed El Sayed Nour El-DeenDepartment of Basic Medical and Dental Sciences, Faculty of Dentistry, Zarqa University, Zarqa, Jordan.
Ahmad Mohamad TahaDepartment of Basic Medical and Dental Sciences, Faculty of Dentistry, Zarqa University, Zarqa, Jordan.
Almoatazbellah ElsayedDepartment of Basic Medical and Dental Sciences, Faculty of Dentistry, Zarqa University, Zarqa, Jordan.
Ahmed Noaman AliDepartment of Basic Medical and Dental Sciences, Faculty of Dentistry, Zarqa University, Zarqa, Jordan.
Reda Samir TahaDepartment of Basic Medical and Dental Sciences, Faculty of Dentistry, Zarqa University, Zarqa, Jordan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study is to evaluate the impacts of apricot kernels and caffeine on blood glucose, lipid profile, insulin secretion, and antioxidant effect in diabetic rats. Forty adult male albino rats were divided into five groups: normal control, diabetic control, diabetic rats treated with apricot kernels, diabetic rats treated with caffeine, and diabetic rats treated with apricot kernels plus caffeine. Fasting samples were collected at the end of the study for analysis, and pieces of liver and pancreatic tissues were removed for histological analysis. There was a significant decrease in blood glucose, glycated hemoglobin, body weight, total cholesterol, triglyceride, and low-density lipoprotein cholesterol (LDL-C) levels and a significant increase in insulin and high-density lipoprotein cholesterol (HDL-C) levels in the kernel and caffeine-treated groups. However, there was little histological alteration in the liver or pancreas, and no significant differences were observed in the histological findings between groups. Overall, it can be concluded that apricot kernel and caffeine had a positive effect in decreasing blood glucose and harmful lipid profile and that caffeine had a synergistic effect on the apricot kernel.

Indexed as

Antioxidantapricot kernelscaffeinenutritariantype 2 diabetes mellitus

Identifiers

PMID39611078
PMCPMC11602279

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.