Evidence map›Paper›PMID 39610984›Full record

ArticleClinical case reports2024

Reversible Cerebral Vasoconstriction Syndrome Following Blood Transfusion in a Patient With Chronic Anemia: A Case Report.

Amogh Verma, Govind Sharma, Ajeet Singh, Harshit Gupta, Deependra Pratap Singh, Abhay M Gaidhane, Mahalaqua Nazli Khatib, Ganesh Bushi, Sanjit Sah, Rodrigue Ndabashinze

Abstract read
In one paragraph

Article in Clinical case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Amogh VermaDepartment of Internal Medicine Rama Medical College Hospital and Research Center Hapur Uttar Pradesh India.ORCID https://orcid.org/0000-0003-2499-4874
Govind SharmaDepartment of Radiology Rama Medical College Hospital and Research Center Hapur Uttar Pradesh India.
Ajeet SinghDepartment of Internal Medicine Dow University of Health Sciences Karachi Pakistan.ORCID https://orcid.org/0009-0009-4090-5393
Harshit GuptaDepartment of Internal Medicine All India Institute of Medical Sciences (AIIMS) Rishikesh Rishikesh India.ORCID https://orcid.org/0000-0002-9737-0563
Deependra Pratap SinghDepartment of Biotechnology Graphic Era Hill University Dehradun India.
Abhay M GaidhaneSchool of Epidemiology and Public Health, Jawaharlal Nehru Medical College and Global Health Academy Datta Meghe Institute of Higher Education Wardha India.
Mahalaqua Nazli KhatibDivision of Evidence Synthesis, Global Consortium of Public Health and Research Datta Meghe Institute of Higher Education Wardha India.
Ganesh BushiCenter for Global Health Research Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University Chennai India.
Sanjit SahDr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth Pune Maharashtra India.
Rodrigue NdabashinzeUniversity of Burundi Bujumbura Burundi.ORCID https://orcid.org/0009-0001-6921-7828

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reversible cerebral vasoconstriction syndrome (RCVS) is a rare neurological disorder characterized by transient constriction and dilation of cerebral arteries, leading to severe headaches and neurological deficits. This case report describes a 41-year-old woman with chronic anemia, acute chronic kidney disease, type 2 diabetes mellitus, and rheumatoid arthritis who developed RCVS following transfusion of packed red blood cells (PRBCs). She experienced sudden-onset seizures and a thunderclap headache 5 days post-transfusion. Diagnostic imaging, including computed tomography (CT) and magnetic resonance imaging (MRI), revealed the characteristic features of vasogenic edema. The patient was treated with blood pressure control and symptomatic relief for pain, resulting in gradual improvement. This case highlights the importance of recognizing RCVS as a potential complication of blood transfusions, particularly in patients with significant comorbidities. Understanding the possible mechanisms, including rapid hemoglobin correction, and the effects of residual plasma and storage lesions in transfused blood, is essential to prevent and manage this rare but serious condition.

Indexed as

blood transfusionchronic anemiaRCVSseizuresthunderclap headachevasogenic edema

Identifiers

PMID39610984
PMCPMC11602260

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.