Evidence map›Paper›PMID 39610980›Full record

ArticleJAC-antimicrobial resistance2024

AmpC β-lactamases detected in Southeast Asian

Tamalee Roberts, Clare L Ling, Wanitda Watthanaworawit, Chanvoleak Cheav, Amphonesavanh Sengduangphachanh, Joy Silisouk, Jill Hopkins, Koukeo Phommasone, Elizabeth M Batty, Paul Turner and 1 more

Abstract read
In one paragraph

Article in JAC-antimicrobial resistance, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Antibiotic resistance inFrontiers in microbiology · 2026
    Review
  4. Article
  5. Article
  6. Genomic insights into extended-spectrumJournal of medical microbiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tamalee RobertsLao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Microbiology Laboratory, Mahosot Hospital, Mahosot Road, Vientiane, Lao PDR.ORCID https://orcid.org/0000-0001-8599-737X
Clare L LingCentre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Wanitda WatthanaworawitShoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand.
Chanvoleak CheavCambodia Oxford Medical Research Unit, Angkor Hospital for Children, Siem Reap, Cambodia.
Amphonesavanh SengduangphachanhLao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Microbiology Laboratory, Mahosot Hospital, Mahosot Road, Vientiane, Lao PDR.
Joy SilisoukLao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Microbiology Laboratory, Mahosot Hospital, Mahosot Road, Vientiane, Lao PDR.
Jill HopkinsCentre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Koukeo PhommasoneLao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Microbiology Laboratory, Mahosot Hospital, Mahosot Road, Vientiane, Lao PDR.
Elizabeth M BattyCentre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Paul TurnerCentre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.ORCID https://orcid.org/0000-0002-1013-7815
Elizabeth A AshleyLao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Microbiology Laboratory, Mahosot Hospital, Mahosot Road, Vientiane, Lao PDR.

Funding

Wellcome Trust
6 · The paper itself

Abstract

Objectives: AmpC β-lactamases are neglected compared with ESBL as a cause of third-generation cephalosporin (3GC) resistance in Enterobacterales in low- and middle-income countries and the burden is unknown. The aim of this study was to investigate the presence of AmpC β-lactamase-producing Methods: Stored clinical isolates of Results: Of 126 isolates collected between 2010 and 2020, 31 (24.6%) and 16 (12.7%) were phenotypically AmpC and inducible AmpC positive by MASTDISCS testing, respectively. All inducible AmpC isolates were ceftriaxone susceptible and 97.7% of AmpC/inducible AmpC isolates tested against cefoxitin were resistant. Through WGS, 17 and eight different STs were detected for the AmpC/inducible AmpC Conclusions: Though uncommon, AmpC and inducible AmpC β-lactamases in

Identifiers

PMID39610980
PMCPMC11604056

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.