Evidence map›Paper›PMID 39610880›Full record

ArticleFrontiers in nutrition2024

Ingestion of 'whole cell' or 'split cell'

Ellen Williamson, Alistair J Monteyne, Ino Van der Heijden, Doaa R Abdelrahman, Andrew J Murton, Benjamin Hankamer, Francis B Stephens, Benjamin T Wall

Registry-linked trialAbstract read
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In one paragraph

Article in Frontiers in nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07791420 (Measurement of Acute Metabolite Changes Following Consumption of Unprocessed and Processed Microalgae), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07791420 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Measurement of Acute Metabolite Changes Following Consumption of Unprocessed and Processed Microalgae: A Randomized Crossover Trial

TypeinterventionalSponsorNational University of SingaporeRan2026 to 2027Enrolled20ConditionsProtein Absorption and Amino Acid Availability, MetabolomicsArmsBead-milled microalgae, Non-bead-milled microalgae, Whey protein isolate, Soy protein isolate, Maltodextrin (Placebo)
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ellen WilliamsonNutritional Physiology Group, Public Health and Sport Sciences, The Medical School, The University of Exeter, Exeter, United Kingdom.
Alistair J MonteyneNutritional Physiology Group, Public Health and Sport Sciences, The Medical School, The University of Exeter, Exeter, United Kingdom.
Ino Van der HeijdenNutritional Physiology Group, Public Health and Sport Sciences, The Medical School, The University of Exeter, Exeter, United Kingdom.
Doaa R AbdelrahmanDepartment of Surgery, University of Texas Medical Branch, Galveston, TX, United States.
Andrew J MurtonDepartment of Surgery, University of Texas Medical Branch, Galveston, TX, United States.
Benjamin HankamerInstitute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia.
Francis B StephensNutritional Physiology Group, Public Health and Sport Sciences, The Medical School, The University of Exeter, Exeter, United Kingdom.
Benjamin T WallNutritional Physiology Group, Public Health and Sport Sciences, The Medical School, The University of Exeter, Exeter, United Kingdom.

Funding

UTMB OAIC Research Education Component (REC)P30AG024832 · NIA · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI JAMES S. GOODWIN, MD, MELISSA M. MORROW · 2005 to 2026
$26.7M
NIA NIH HHS P30 AG024832
6 · The paper itself

Abstract

Introduction: Microalgae provide a sustainable basis for protein-rich food production. However, human data concerning microalgae ingestion, subsequent postprandial amino acid (AA) availability and associated metabolic responses are minimal. Objectives: We investigated ingesting Subjects/methods: Ten participants (age; 21 ± 1y, BMI; 25 ± 1 kg·m Results: Protein ingestion increased plasma AA concentrations ( Conclusion: Our data imply that microalgae can present a bioavailable source of protein for human nutrition, however, challenges remain, requiring species selection and/or biomass processing to overcome.

Indexed as

algal proteinalternative proteinmicroalgae proteinprotein ingredientsustainable food

Identifiers

PMID39610880
PMCPMC11602285

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.