Evidence map›Paper›PMID 39610842›Full record

ArticleFrontiers in endocrinology2024

Inflammatory Th17 cells are correlated with insulin resistance and erythrocyte parameters in overweight and obese children.

Dorota Artemniak-Wojtowicz, Małgorzata Rumińska, Anna Stelmaszczyk-Emmel, Monika Paluchowska, Beata Ewa Pyrżak, Anna Małgorzata Kucharska

Abstract read
In one paragraph

Article in Frontiers in endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Implications of adipocyte dysfunction in pediatric obesity: a narrative review.Pediatric endocrinology, diabetes, and metabolism · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dorota Artemniak-WojtowiczDepartment of Pediatrics and Endocrinology, Medical University of Warsaw, Warsaw, Poland.
Małgorzata RumińskaDepartment of Pediatrics and Endocrinology, Medical University of Warsaw, Warsaw, Poland.
Anna Stelmaszczyk-EmmelDepartment of Laboratory Diagnostics and Clinical Immunology of Developmental Age, Faculty of Medicine, Medical University of Warsaw, Warsaw, Poland.
Monika PaluchowskaDepartment of Pediatrics and Endocrinology, Medical University of Warsaw, Warsaw, Poland.
Beata Ewa PyrżakDepartment of Pediatrics and Endocrinology, Medical University of Warsaw, Warsaw, Poland.
Anna Małgorzata KucharskaDepartment of Pediatrics and Endocrinology, Medical University of Warsaw, Warsaw, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Obesity is thought to be accompanied by chronic, low-grade, inflammation. The adipocytes are present in the subcutaneous and visceral fat tissue and contribute to the bone marrow cell compartment. Therefore, it poses a question whether the factors influencing adipocyte functions also have an impact on the hematopoietic function of the bone marrow. The aim of our study was to evaluate the association between erythrocyte parameters, the proinflammatory Th17 lymphocytes, and IR markers in children with excessive body weight. Methods: A total of 27 overweight/obese and 15 normal-weight children aged 8-18 years were enrolled in the study. The analysis included anthropometric measurements, evaluation of Th17 cell frequency, erythrocyte parameters, and carbohydrate metabolism parameters. Results: In overweight/obese children, erythrocyte count ( Conclusions: Our study confirmed that the erythrocyte parameters are higher in children with obesity and are positively correlated with insulin resistance and proinflammatory Th17 lymphocyte. Thus, it can be concluded that erythrocyte parameters reflect the risk of developing IR in response to chronic inflammation associated with obesity. These are simple, easily accessible, and repeatable tests that, in the assessment of obese patients, may herald the developing metabolic syndrome and serve as a helpful additional tool for assessing the effectiveness of treatment.

Indexed as

ErythrocytesInsulin ResistanceOverweightPediatric ObesityTh17 CellsAdolescentBiomarkersChildErythrocyte CountFemaleHumansInflammationMaleBiomarkerschildrenerythrocyteinflammationinsulin resistanceobesityTh17 cells

Identifiers

PMID39610842
PMCPMC11602275

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.