Evidence map›Paper›PMID 39610833›Full record

ArticleBiochemistry and biophysics reports2024

Sophoricoside reduces inflammation in type II collagen-induced arthritis by downregulating NLRP3 signaling.

Youyang Liu, Yunlu Zhao, Qi Guo, Pengfei Wang, Peixuan Li, Qingqing Du, Huazhou Xu, Qingyin Yu, Xiaoyi Zhao, Weiya Zhang and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry and biophysics reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Role of isoflavones in multiple sclerosis.IBRO neuroscience reports · 2025
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Youyang LiuSchool of Basic Medicine, Hebei University of Chinese Medicine, Shijiazhuang, 050200, Hebei, China.
Yunlu ZhaoDepartment of Cardiovascular Diseases, Shinshu University School of Medicine, Matsumoto, 390-8621, Japan.
Qi GuoDepartment of Molecular and Cellular Physiology, Shinshu University School of Medicine, Matsumoto, 390-8621, Japan.
Pengfei WangDepartment of Cardiology, The Second Hospital of Hebei Medical University, Shijiazhuang, 050000, Hebei, China.
Peixuan LiDepartment of Cardiovascular Diseases, Shinshu University School of Medicine, Matsumoto, 390-8621, Japan.
Qingqing DuSchool of Basic Medicine, Hebei University of Chinese Medicine, Shijiazhuang, 050200, Hebei, China.
Huazhou XuResearch Central, Hebei University of Chinese Medicine, Shijiazhuang, 050200, Hebei, China.
Qingyin YuSchool of Basic Medicine, Hebei University of Chinese Medicine, Shijiazhuang, 050200, Hebei, China.
Xiaoyi ZhaoHebei Provincial Engineering Laboratory of Plant Bioreactor Preparation Technology, No. 326 Xinshi South Road, Qiaoxi District, Shijiazhuang, 050090, Hebei, China.
Weiya ZhangHebei Provincial Engineering Laboratory of Plant Bioreactor Preparation Technology, No. 326 Xinshi South Road, Qiaoxi District, Shijiazhuang, 050090, Hebei, China.
Shengjun AnHebei Provincial Engineering Laboratory of Plant Bioreactor Preparation Technology, No. 326 Xinshi South Road, Qiaoxi District, Shijiazhuang, 050090, Hebei, China.
Shuhui WuSchool of Basic Medicine, Hebei University of Chinese Medicine, Shijiazhuang, 050200, Hebei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune responses, especially NLRP3 signaling in macrophages, play critical roles in rheumatoid arthritis (RA), an autoimmune and inflammatory disease. In this study, we aimed to identify novel therapies for RA. We focused on sophoricoside (SOP), an isoflavone glycoside isolated from

Indexed as

Collagen-induced arthritisInflammationMacrophagesNLRP3Rheumatoid arthritisSophoricoside

Identifiers

PMID39610833
PMCPMC11603010

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.