Evidence map›Paper›PMID 39610552›Full record

ArticleJournal of diabetes and metabolic disorders2024

Allele frequency of genetic variations related to the

Negar Sarhangi, Noushin Fahimfar, Fatemeh Rouhollah, Farshad Sharifi, Mohammad Bidkhori, Shekoufeh Nikfar, Afshin Ostovar, Iraj Nabipour, George P Patrinos, Mandana Hasanzad

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of diabetes and metabolic disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Negar SarhangiMedical Genomics Research Center, Tehran Medical Sciences, Islamic Azad University, Tehran, 1916893813 Iran.ORCID 0000-0003-2385-7333
Noushin FahimfarOsteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.ORCID 0000-0001-6205-9794
Fatemeh RouhollahMedical Genomics Research Center, Tehran Medical Sciences, Islamic Azad University, Tehran, 1916893813 Iran.
Farshad SharifiElderly Health Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, 1411713119 Iran.ORCID 0000-0002-2035-6587
Mohammad BidkhoriMetabolomics and Genomics Research Center, Endocrinology and Metabolism Molecular- Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Shekoufeh NikfarEndocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, 1411713119 Iran.ORCID 0000-0002-5206-6197
Afshin OstovarOsteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.ORCID 0000-0001-8670-5797
Iraj NabipourThe Persian Gulf Tropical Medicine Research Center, The Persian Gulf Biomedical Sciences Research Institute, Bushehr University of Medical Sciences, Bushehr, Iran.ORCID 0000-0002-1785-0883
George P PatrinosSchool of Health Sciences, Department of Pharmacy, University of Patras, Patras, Greece.ORCID 0000-0002-0519-7776
Mandana HasanzadPersonalized Medicine Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-0538-1135

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The efficacy and safety of drug treatments vary widely due to genetic variations. Pharmacogenomics investigates the impact of genetic variations on patient drug response. This research investigates the frequency of Methods: The study was conducted using the data of the Bushehr Elderly Health (BEH) program, a population-based cohort study of the elderly population aged ≥ 60 years. Genotyping of three Results: The genotyping analysis revealed significant differences compared to major global populations that were addressed in the gnomAD database. Conclusions: The

Indexed as

Allele frequencyGenetic variationIranPharmacogeneticUGT1A1

Identifiers

PMID39610552
PMCPMC11599689

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.