Evidence map›Paper›PMID 39610333›Full record

ReviewTransfusion2025

Privacy-preserving federated data access and federated learning: Improved data sharing and AI model development in transfusion medicine.

Na Li, Antoine Lewin, Shuoyan Ning, Marianne Waito, Michelle P Zeller, Alan Tinmouth, Andrew W Shih, Canadian Transfusion Trials Group

Abstract readReview
In one paragraph

Review in Transfusion, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. AI and Blood Banking: Predicting Transfusion Demand - A Systematic Review of Forecasting Approaches.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Na LiDepartment of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.ORCID https://orcid.org/0000-0002-4803-0984
Antoine LewinMedical Affairs and Innovation, Héma-Québec, Montreal, Quebec, Canada.ORCID https://orcid.org/0000-0003-1748-4198
Shuoyan NingMichael G. DeGroote Centre for Transfusion Research, McMaster University, Hamilton, Ontario, Canada.ORCID https://orcid.org/0000-0002-7675-4058
Marianne WaitoIntegrated Supply Chain Planning, Canadian Blood Services, Ottawa, Ontario, Canada.
Michelle P ZellerMichael G. DeGroote Centre for Transfusion Research, McMaster University, Hamilton, Ontario, Canada.
Alan TinmouthDepartment of Medicine, The Ottawa Hospital, Ottawa, Ontario, Canada.
Andrew W ShihDepartment of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.
Canadian Transfusion Trials Group

Funding

Alberta Innovates AI Advance - NSERC Alliance 2022/23Canadian Blood ServicesNatural Sciences and Engineering Research Council of Canada RGPIN-2022-02999
6 · The paper itself

Abstract

backgroundHealth data comprise data from different aspects of healthcare including administrative, digital health, and research-oriented data. Together, health data contribute to and inform healthcare operations, patient care, and research. Integrating artificial intelligence (AI) into healthcare requires understanding these data infrastructures and addressing challenges such as data availability, privacy, and governance. Federated learning (FL), a decentralized AI training approach, addresses these challenges by allowing models to learn from diverse datasets without data leaving its source, thus ensuring privacy and security are maintained. This report introduces FL and discusses its potential in transfusion medicine and blood supply chain management. METHODS AND DISCUSSION: FL can offer significant benefits in transfusion medicine by enhancing predictive analytics, personalized medicine, and operational efficiency. Predictive models trained on diverse datasets by FL can improve accuracy in forecasting blood transfusion demands. Personalized treatment plans can be refined by aggregating patient data from multiple institutions using FL, reducing adverse reactions and improving outcomes. Operational efficiency can also be achieved through precise demand forecasting and optimized logistics. Despite its advantages, FL faces challenges such as data standardization, governance, and bias. Harmonizing diverse data sources and ensuring fair, unbiased models require advanced analytical solutions. Robust IT infrastructure and specialized expertise are needed for successful FL implementation.

conclusionFL represents a transformative approach to AI development in healthcare, particularly in transfusion medicine. By leveraging diverse datasets while maintaining data privacy, FL has the potential to enhance predictions, support personalized treatments, and optimize resource management, ultimately improving patient care and healthcare efficiency.

Indexed as

Artificial IntelligenceBlood TransfusionInformation DisseminationPrivacyTransfusion MedicineFederated LearningHumansPrecision Medicineblood managementhealth research methodologystatisticsstudy design

Identifiers

PMID39610333
PMCPMC11747086

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.