Evidence map›Paper›PMID 39609928›Full record

ArticleTrials2024

Agile monitoring dashboard for clinical research studies.

Leslie Gardner, Peggy Bylund, Sarah Robbins, Emma Holler, Fereshtehossadat Shojaei, Fatemehalsadat Shojaei, Mark Seidman, Richard J Holden, Nicole R Fowler, Ben Zarzaur and 2 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05373017 (Delirium and Neuropsychological Recovery Among Emergency General Surgery Survivors), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05373017 naactive not recruitingnot on this map

Delirium and Neuropsychological Recovery Among Emergency General Surgery Survivors (DANE)

TypeinterventionalSponsorUniversity of Wisconsin, MadisonRan2023 to 2027Enrolled528ConditionsDeliriumArmsDANE Recovery Program, Questionnaires
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Leslie GardnerCenter for Health Innovation and Implementation Science, School of Medicine, Indiana University, Indianapolis, IN, USA. lesgard@iu.edu.ORCID http://orcid.org/0009-0005-3883-6393
Peggy BylundCenter for Health Innovation and Implementation Science, School of Medicine, Indiana University, Indianapolis, IN, USA.
Sarah RobbinsSchool of Medicine and Public Health, University of Wisconsin, Madison, WI, USA.
Emma HollerSchool of Medicine, Indiana University, Indiana University, Indianapolis, IN, USA.
Fereshtehossadat ShojaeiComputing, and Engineering, Luddy School of Informatics, Indiana University Bloomington, Bloomington, IN, USA.
Fatemehalsadat ShojaeiCenter for Health Innovation and Implementation Science, School of Medicine, Indiana University, Indianapolis, IN, USA.
Mark SeidmanCenter for Health Innovation and Implementation Science, School of Medicine, Indiana University, Indianapolis, IN, USA.
Richard J HoldenCenter for Health Innovation and Implementation Science, School of Medicine, Indiana University, Indianapolis, IN, USA.
Nicole R FowlerCenter for Health Innovation and Implementation Science, School of Medicine, Indiana University, Indianapolis, IN, USA.
Ben ZarzaurSchool of Medicine and Public Health, University of Wisconsin, Madison, WI, USA.
Cristina BarboiSchool of Medicine, Indiana University, Indiana University, Indianapolis, IN, USA.
Malaz BoustaniCenter for Health Innovation and Implementation Science, School of Medicine, Indiana University, Indianapolis, IN, USA.

Funding

Emergency General Surgery Delirium Recovery Model: A Collaborative Care InterventionR01AG076489 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI MALAZ BOUSTANI, Ben L Zarzaur · 2022 to 2026
$10.2M
NIA NIH HHS R01 AG076489
6 · The paper itself

Abstract

backgroundClinical trial success hinges on efficient participant recruitment and retention. However, slow accrual and attrition frequently hinder progress. To address these challenges, a novel dashboard tool with control charts has been developed to provide investigators on the multi-site study of Delirium and Neuropsychological Recovery among Emergency General Surgery Survivors (DANE study) with timely information to improve trial recruitment.

methodsA quality monitoring Excel dashboard with control chart functionality developed by the principal investigator's (PI) group and implemented in a department of a large hospital was re-engineered for research study recruitment purposes. The dashboard provides the PIs and other stakeholders with timely, actionable, and unbiased information on the count of participants who have completed each stage or action within the process, the rates of completion and trends, both for the current week and cumulatively.

resultsThe DANE dashboard was prototyped using Microsoft Excel for accessibility and rapid development. The tool integrates with a REDCap database, simplifying data import and analysis. By facilitating informed decision-making throughout the recruitment process, the DANE dashboard has significantly enhanced clinical trial efficiency and led to changes in the eligibility criteria and improvements in the approach and consent processes.

conclusionsThe DANE dashboard for monitoring participant recruitment and attrition in research studies represents a significant step towards enhancing study management and decision-making processes. It can be adapted to other clinical studies and other staged processes with attrition. The generic version, currently under development, holds promise for evolving into a valuable simulator by incorporating a spreadsheet for generating random data and accounting for resource constraints. This enhancement could further be augmented by integrating forecasting capabilities into the control charts.

trial registrationThe Delirium and Neuropsychological Recovery among Emergency General Surgery Survivors (DANE) study (NCT05373017, 1R01AG076489-01) is a multi-site, two-arm, single-blinded randomized controlled clinical trial to evaluate the efficacy of the Emergency General Surgery (EGS) Delirium Recovery Model to improve the cognitive, physical, and psychological recovery of EGS delirium survivors over 65. The DANE study received approval from the University of Wisconsin-Madison/University of Wisconsin Hospitals and Clinics Institutional Review Board (IRB, no. 2022-0545, approval date September 14, 2022), and Indiana University agreed to cede IRB review to University of Wisconsin-Madison/University of Wisconsin Hospital and Clinics (September 29, 2022).

Indexed as

Patient SelectionBiomedical ResearchDeliriumHumansMulticenter Studies as TopicResearch DesignAccrualClinical trial recruitmentControl chartDashboard

Identifiers

PMID39609928
PMCPMC11606209

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.