Evidence map›Paper›PMID 39609872›Full record

SynthesisJournal of orthopaedic surgery and research2024

Comparison of clinical outcomes between hamstring tendon autografts and hybrid grafts in ACL reconstruction: a systematic review and meta-analysis.

Lei Fan, Lei Zhang, Jiexi Tang, Zhe Xu, Weili Fu

Abstract readSystematic ReviewMeta-AnalysisComparative Study
In one paragraph

Synthesis in Journal of orthopaedic surgery and research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Knee proprioception following anterior cruciate ligament repair and reconstruction: A systematic review and network meta-analysis.Asia-Pacific journal of sports medicine, arthroscopy, rehabilitation and technology · 2026
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lei Fan *Department of Orthopedics, Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, China.
Lei Zhang *Department of Orthopedics, Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, China.
Jiexi TangDepartment of Orthopedics, Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, China.
Zhe XuDepartment of Orthopedics, Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, China.
Weili FuDepartment of Orthopedics, Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, China. foxwin2008@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHamstring tendon (HT) autografts have become a popular choice for anterior cruciate ligament (ACL) reconstruction. However, small-diameter grafts are inevitably encountered during surgery, which have poor biomechanical properties. Hybrid grafts (HGs) using an allograft combined with small diameter HT are gaining interest from surgeons. HYPOTHESIS: There would be no difference between the HT autograft and HG in terms of failure, knee stability, and patient-reported outcomes. STUDY

designSystematic review and meta-analysis; Level of evidence, 4.

methodsThe PubMed, Embase, web of science and Cochrane databases were systematically searched from their inception until July 1, 2022. Clinical trials that compared HG and HT autografts were included. The quality of the included studies was assessed with the Cochrane Collaboration's risk of bias tool and the modified Newcastle-Ottawa Scale. Extracted data were pooled with fixed or random effects depending on the detected heterogeneity.

resultsA total of 14 eligible studies involving 1411 patients (HT: 863; HG: 548) were included in the quantitative meta-analysis. The mean age of the patients involved ranged from 14.6 to 40.4 years. Compared to patients who received HT autografts, patients receiving HGs had similar postoperative failure rate (OR, 0.99; P = 0.97; I

conclusionThis review found no significant differences in failure rates, knee stability, or patient-reported outcomes between autologous HT and HG in ACLR. Surgeons should prioritize autografts of adequate size through optimized techniques and consider hybrid grafts as a last resort, considering the risks associated with allografts.

Indexed as

Anterior Cruciate Ligament ReconstructionAutograftsHamstring TendonsAdolescentAdultAnterior Cruciate Ligament InjuriesFemaleHumansMalePatient Reported Outcome MeasuresTransplantation, AutologousTreatment OutcomeYoung AdultAnterior cruciate ligament reconstructionAutograftHamstring tendonHybrid graftMeta-analysis

Identifiers

PMID39609872
PMCPMC11606057

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.