Evidence map›Paper›PMID 39609790›Full record

ArticleJournal of neurodevelopmental disorders2024

Cortical Vision Impairment (CVI)-informed assessment and treatment of challenging behavior in a child with SCN2A-related disorder.

Benjamin R Thomas, Natasha N Ludwig, Danielle Pelletier, Melanie Bauer, Rebecca Hommer, Constance Smith-Hicks, Julia T O'Connor

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neurodevelopmental disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Visual function and autism spectrum disorder.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Review
  2. Article
  3. Degraded sensory coding in a mouse model ofbioRxiv : the preprint server for biology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Benjamin R ThomasDepartment of Behavioral Psychology, Kennedy Krieger Institute, Baltimore, MD, USA. Benjamin.thomas2@nationwidechildrens.org.ORCID 0000-0001-6866-7854
Natasha N LudwigDepartment of Neuropsychology, Kennedy Krieger Institute, Baltimore, MD, USA.ORCID 0000-0002-8934-7267
Danielle PelletierDepartment of Behavioral Psychology, Kennedy Krieger Institute, Baltimore, MD, USA.
Melanie BauerDepartment of Behavioral Psychology, Kennedy Krieger Institute, Baltimore, MD, USA.
Rebecca HommerConnections Beyond Sight and Sound, University of Maryland, College Park, MD, USA.
Constance Smith-HicksDepartment of Neurology and Developmental Medicine, Kennedy Krieger Institute, Baltimore, MD, USA.ORCID 0000-0001-8241-9574
Julia T O'ConnorDepartment of Behavioral Psychology, Kennedy Krieger Institute, Baltimore, MD, USA.ORCID 0000-0001-9102-0629

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This report presents results of parent-implemented behavioral treatments for a child with cortical visual impairment (CVI), intellectual disability (ID), epilepsy, and autism spectrum disorder (ASD) associated with a pathogenic variant in the SCN2A gene (i.e., SCN2A-Related Disorder). Treatment evaluations were informed by combined results of functional behavior assessment (FBA) and functional vision assessment (FVA) which yielded CVI-related accommodations. The treatment of escape-maintained challenging behavior involved the evaluation of behavioral prompting strategies in accordance with CVI-related accommodations, extinction (EXT), and differential reinforcement modifications. The treatment for behavior problems maintained by access to food (tangible-edible) included functional communication training (FCT), EXT, and schedule thinning with schedule-correlated visual signals. Overall, integrating child-specific CVI-related accommodations was essential for developing effective behavioral interventions for this child. FVAs are accessible and practical for uptake by behavior analysts in vision-informed assessment and treatment of challenging behavior.

Indexed as

Autism Spectrum DisorderIntellectual DisabilityNAV1.2 Voltage-Gated Sodium ChannelBehavior TherapyChildEpilepsyHumansProblem BehaviorVision DisordersNAV1.2 Voltage-Gated Sodium ChannelSCN2A protein, humanApplied behavior analysisAutism spectrum disorderCortical visual impairmentFunctional behavior assessmentFunctional vision assessmentParent trainingSCN2A-related disorder

Identifiers

PMID39609790
PMCPMC11603671

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.