SynthesisBMC oral health2024
Remineralization and anti-demineralization effect of orthodontic adhesives on enamel surrounding orthodontic brackets: a systematic review of in vitro studies.
Synthesis in BMC oral health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Nanoparticle-Enriched Sodium Fluoride Gel with and Without Er, Cr: YSGG Laser Activation: Effects on Enamel Microhardness and Sealant Bond Performance on Demineralized Enamel.Gels (Basel, Switzerland) · 2026Article
- Enhanced remineralization and acid resistance of white spot lesions by combined bioactive glass and resin infiltration: an in vitro study.BMC oral health · 2026Article
- Evaluation of an orthodontic adhesive containing 2 wt% nano-hydroxyapatite synthesized from a biogenic calcium precursor: antibacterial activity, calcium ion concentration, and enamel demineralization.Biomaterial investigations in dentistry · 2026Article
- The influence of incorporation of hydroxyapatite/collagen nanocomposite into glass ionomer cement on surface roughness, microhardness, and fluoride-ion release potential.BMC oral health · 2025Article
- The effect of nanohydroxyapatite serum and toothpaste on prevention of enamel demineralization around orthodontic brackets: an in vitro study.BMC oral health · 2025Article
- Orthodontic Bracket Removal and Enamel Roughness: Comparing the Effects of Sapphire and Metallic Brackets in an In Vitro Study.Bioengineering (Basel, Switzerland) · 2025Article
- Microscopic and Crystallographic Analysis of Increased Acid Resistance of Melted Dental Enamel Using 445 nm Diode Laser: An Ex-Vivo Study.Dentistry journal · 2025Article
- The impact of fluorinated graphene versus nanohydroxyapatite crystals on artificial white spot lesion microhardness and color change.BMC oral health · 2025Article
- Research on the prevention of tooth demineralization and the effects and mechanisms of different mineralization solutions on the metabolism ofFrontiers in oral health · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWhite spot lesions are initial sign of enamel caries that compromise esthetic appearance following orthodontic treatment. Thus, the systematic review was conducted to evaluate the remineralization potential of orthodontic adhesives on early-enamel lesions surrounding orthodontic bracket.
methodsSearch strategy was performed through three databases (PubMed, Web of Science, and Scopus). A total number of 1712 studies were identified for being potentially relevant, 62 among them were further assessed. Finally, 24 studies were included in this systematic review after adopting the eligibility criteria. The methodologies used to assess enamel remineralization were micro-computed tomography, cross-sectional microhardness, and polarized light microscopy for evaluating remineralization extent; surface microhardness, color change, and laser-induced fluorescence for evaluating superficial surface mineralization; Fourier Transform InfraRed, and Energy Dispersive Spectroscopy technique for chemical characterization.
resultsBioactive glass (BAG), nano-hydroxyapatite (n-HAP), nano-amorphous calcium phosphate (n-ACP), nano-calcium fluoride (n-CaF
conclusionThe outcome of the included studies supports the effectiveness of incorporation of remineralizing agents into orthodontic adhesives.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.