SynthesisBMC geriatrics2024
Association of motoric cognitive risk syndrome with depression in older adults: a meta-analysis and systematic review of cross-sectional and cohort studies.
Synthesis in BMC geriatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Depression and health outcomes: An umbrella review of systematic reviews and meta-analyses of observational studies.Translational psychiatry · 2025Pooled it
- Sensor-Based Assessment of Groove Music and Sports Dance on Cognitive-Emotional and Neuromuscular Functions in Older Adults.Sensors (Basel, Switzerland) · 2025Trial
- Prevalence and Influencing Factors of Motoric Cognitive Risk Syndrome Among Older Adults in Long-Term Care Facilities.Healthcare (Basel, Switzerland) · 2026Article
- Association between depressive symptom trajectories and motoric cognitive risk syndrome in older adults: a cohort study.BMC geriatrics · 2026Article
- Observational
- Differential dementia risks of motoric cognitive risk syndrome and mild cognitive impairment among older adults in China: a 7-year cohort study.BMC geriatrics · 2025Article
- Nonlinear association between TyG-related Indices and motoric cognitive risk syndrome in depressive individuals: evidence from the CHARLS study.Frontiers in psychiatry · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundIn an aging society, depression has become a public health challenge that can lead to many adverse health outcomes; evidence addressing the link between depression and motor cognitive risk syndrome (MCR, a novel syndrome that effectively predicts dementia) is still lacking.
methodsA PRISMA checklist was used to systematically review the relevant peer-reviewed literature for the primary data analysis. A computer search of CNKI, Wan Fang Data, CBM, VIP, PubMed, Web of Science, Embase, Cochrane Library, Scopus, and Ovid databases, all from creation to March 15, 2023. A meta-analysis was conducted using Stata 17.0, the Newcastle-Ottawa Scale instrument (NOS), and the Agency for Healthcare Research and Quality (AHRQ) for quality appraisal. We used Q and I
resultThirteen studies were included, including seven cross-sectional studies and six cohort studies, and data on the association between depression and MCR in the elderly were extracted. Moreover, the results of the meta-analysis showed that there was a significant correlation between depression and MCR in the cross-sectional study [OR = 2.43, 95% CI(1.31 ~ 3.54), P < 0.01]. In the cohort study, depression in the elderly was associated with the occurrence of MCR [HR = 1.19, 95% CI(1.08 ~ 1.30), P < 0.01]; Subgroup analysis by age, depression assessment tool, MCR assessment tool, and follow-up time (cohort study only) showed statistically significant differences (P < 0.01).
conclusionMeta-analysis of cross-sectional studies and cohort studies showed that depression in older adults was associated with the development of MCR, and depression increased the risk of MCR in older adults.
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