Evidence map›Paper›PMID 39609742›Full record

ArticleBMC ophthalmology2024

Evaluating anterior corneal surface using Placido ring mires for irregular astigmatism in refractory corneal subepithelial infiltrates after adenoviral conjunctivitis.

Noriko Toyokawa, Kaoru Araki-Sasaki, Hideya Kimura, Shinichiro Kuroda

Abstract readCase Reports
In one paragraph

Article in BMC ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Noriko ToyokawaNagata Eye Clinic, 1147 Kitayamada Hohrai, Nara-City, 6310844, Nara, Japan. noritama0620@topaz.ocn.ne.jp.
Kaoru Araki-SasakiNagata Eye Clinic, 1147 Kitayamada Hohrai, Nara-City, 6310844, Nara, Japan.
Hideya KimuraNagata Eye Clinic, 1147 Kitayamada Hohrai, Nara-City, 6310844, Nara, Japan.
Shinichiro KurodaNagata Eye Clinic, 1147 Kitayamada Hohrai, Nara-City, 6310844, Nara, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCorneal subepithelial infiltrates (SEIs) are characteristic clinical findings of adenoviral keratoconjunctivitis (AKC). In eyes with SEIs, both corneal opacity and irregular astigmatism may interfere with vision. However, irregular astigmatism is often overlooked in patients with AKC. Here, we report a case of decreased vision due to irregular corneal surfaces detected by Placido ring mires in eyes with corneal SEIs after AKC. CASE PRESENTATION: An 8-year-old girl with decreased vision was referred to our clinic. She had been diagnosed with AKC two years prior by a different physician. Thereafter, she experienced recurring episodes of decreased vision, epiphora, and photophobia in both eyes. The symptoms persisted despite resolution of the corneal opacity with steroid eye drops. Despite mild corneal opacity, both eyes exhibited distorted Placido ring patterns on corneal topography. The decreased vision in both eyes was due to the irregular corneal surface caused by SEIs, rather than corneal opacity. Topical 0.1% tacrolimus eye drops were effective in treating corneal opacity and irregular corneal surfaces.

conclusionsOur findings highlight that vision loss due to SEIs after AKC may stem from an irregular corneal surface regardless of corneal opacity severity, and the usefulness of a conventional and simple topography using Placido rings during treatment with 0.1% tacrolimus eye drops for SEIs in AKC.

Indexed as

Adenovirus Infections, HumanAstigmatismCorneal TopographyEye Infections, ViralKeratoconjunctivitisChildConjunctivitis, ViralEpithelium, CornealFemaleHumansImmunosuppressive AgentsTacrolimusVisual AcuityImmunosuppressive AgentsTacrolimusAdenoviral keratoconjunctivitisIrregular astigmatismPlacido ring miresSubepithelial corneal infiltrates

Identifiers

PMID39609742
PMCPMC11603996

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.