ArticleJournal of medical case reports2024
The effect of binaural pulse modulation (B.P.M) on brain state in depression and anxiety: a case series.
Article in Journal of medical case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Binaural Pulse Modulation (BPM) as an Adjunctive Treatment for Anxiety: A Pilot Study.Brain sciences · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveIn this pilot study a binaural pulse modulator was tested to see if it leads to a change in self-reported measures of distress. This binaural pulse modulator produces two frequencies that combine to create a binaural pulse to stimulate the nervous system through a differential auditory tone presentation and the response of the user can be adjusted to the appropriate target tone for effective treatment use. Each individual calibrated the binaural pulse to increase the level of emotion experienced while imagining an experience with a similar emotional valence or while engaged in a cognitive function while also listening to the sound. "Treatment" is based on the client's control of the binaural pulses to achieve the desired state. Training focuses on specific aspects of their psychological difficulties while listening to an auditory tone, turning a knob until the sound becomes uncomfortable. Finally, another knob is turned to cancel out the uncomfortable noise which appears to be associated with a reduction in distress. CASE PRESENTATIONS: Four adult Hispanic participants (three females and one male) were studied with self-reported measures of distress (generalized anxiety disorder 7, Coronavirus Disease Stress Scale, posttraumatic stress disorder checklist for Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, and Beck depression scale II) were completed at screening, before treatment, after treatment, 4-weeks post-treatment, and 12-weeks post-treatment. Quantitative electroencephalogram and functional magnetic resonance imaging were also performed before and after treatment.
resultsPreliminary findings indicated that at the end of treatment with binaural pulse modulator there were reported reductions in self-reported levels of distress. Quantitative electroencephalogram as well as functional magnetic resonance imaging changes in brain state were also noted when comparing pre- to post-treatment.
conclusionsbinaural pulse modulator use appears to result in temporary changes in self-reported levels of distress during treatment. Limitations of the study are reviewed and directions for further research are offered.
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