Evidence map›Paper›PMID 39609599›Full record

Observational studyEye (London, England)2025

Effectiveness of interventions for convergence insufficiency: an observational study evaluating clinical outcomes and health-related quality of life using AS20.

Joel Lee Zher Jong, Zainab Saleem, Joshua Simmons, Martin Rhodes, Jessy Choi

Abstract readObservational Study
In one paragraph

Observational study in Eye (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joel Lee Zher JongSchool of Medicine and Population Health, University of Sheffield, Sheffield, UK. joel.jong@nhs.net.ORCID http://orcid.org/0000-0002-8339-2083
Zainab SaleemDepartment of Orthoptics, Royal Hallamshire Hospital, Sheffield Teaching Hospital NHS Foundation Trust, Sheffield, UK.
Joshua SimmonsDepartment of Orthoptics, Royal Hallamshire Hospital, Sheffield Teaching Hospital NHS Foundation Trust, Sheffield, UK.
Martin RhodesDepartment of Orthoptics, Royal Hallamshire Hospital, Sheffield Teaching Hospital NHS Foundation Trust, Sheffield, UK.
Jessy ChoiSchool of Medicine and Population Health, University of Sheffield, Sheffield, UK.ORCID http://orcid.org/0000-0002-1874-1953

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundConvergence insufficiency (CI) is a common condition that can impair visual performance and comfort during close visual work. This observational study evaluated the effectiveness of interventions on clinical outcomes and health-related quality-of-life using the Adult Strabismus-20 (AS20) questionnaire in patients with CI.

methodsData was extracted from a database collected at first consultation from 2015 to 2022. Demographics, interventions and outcomes of 75 patients with CI (mean age 47.2 ± 24.7 years) were analysed.

resultsOrthoptic exercises were prescribed to 58% of patients, 28% received prisms and 9% received no treatment. At the latest follow-up review, 24% were recommended to continue exercises, 24% had prisms, 1 underwent bimedial resection and 1 had treatment with Botulinum Toxin A (BTXA). The median follow-up was 5.0 (0-55) months, 100% were discharged with 25% following failure-to-attend and 11% died. At the latest follow-up, the attendance failure rate was higher for exercises (36%) than for prisms (10%). Both near-prism cover test and near-point of convergence improved from a median of 12 (95% CI 10-14) prism dioptres (PD) to 8.5 (95% CI 6-12) PD, and 17.5 (95%CI 15-20) cm to 10.0 (95%CI 8.3-12.0) cm respectively (p < 0.05). Near-prism fusion range also improved from 10(95%CI 8-14) PD to 16(95% CI 12-20) PD (p < 0.05). The median AS20 score at presentation were 100/100 (30-100) and 47.5/100 (0-100), and post-intervention were 100/100 (75-100) and 70/100 (12.5-97.5) for psychosocial and functional components, respectively.

conclusionThis cohort offers valuable insights into the real-life clinical management of CI in a tertiary adult strabismus centre. However, the study also found that long-term compliance with treatment is intrinsically challenging, emphasising the importance of disease education.

Indexed as

Convergence, OcularOcular Motility DisordersOrthopticsQuality of LifeAdultAgedBotulinum Toxins, Type AEyeglassesFemaleFollow-Up StudiesHumansMaleMiddle AgedRetrospective StudiesSurveys and QuestionnairesTreatment OutcomeBotulinum Toxins, Type A

Identifiers

PMID39609599
PMCPMC11933397

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.