Evidence map›Paper›PMID 39609392›Full record

ArticleNature communications2024

Late-stage (radio)fluorination of alkyl phosphonates via electrophilic activation.

Kaiqiang Zhang, Wanru Feng, Zhaobiao Mou, Lei Zhang, Mengting Ma, Zixiao Zhao, Xia Liu, Xiaoyuan Chen, Zijing Li

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kaiqiang Zhang *State Key Laboratory of Vaccines for Infectious Diseases, Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, Fujian, China.
Wanru Feng *State Key Laboratory of Vaccines for Infectious Diseases, Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, Fujian, China.
Zhaobiao Mou *State Key Laboratory of Vaccines for Infectious Diseases, Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, Fujian, China.
Lei ZhangTianjin Engineering Technology Center of Chemical Wastewater Source Reduction and Recycling, School of Science, Tianjin Chengjian University, Tianjin, China.
Mengting MaState Key Laboratory of Vaccines for Infectious Diseases, Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, Fujian, China.
Zixiao ZhaoState Key Laboratory of Vaccines for Infectious Diseases, Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, Fujian, China.
Xia LiuState Key Laboratory of Vaccines for Infectious Diseases, Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, Fujian, China.
Xiaoyuan ChenDepartments of Diagnostic Radiology, Surgery, Chemical and Biomolecular Engineering, and Biomedical Engineering, Yong Loo Lin School of Medicine and College of Design and Engineering, National University of Singapore, Singapore, Singapore.ORCID 0000-0002-9622-0870
Zijing LiState Key Laboratory of Vaccines for Infectious Diseases, Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, Fujian, China. zijing.li@xmu.edu.cn.ORCID 0000-0003-2156-6479

Funding

MOH | National Medical Research Council (NMRC) CG21APR1005MOH | National Medical Research Council (NMRC) MOH-001041MOH | National Medical Research Council (NMRC) MOH-001388-00National Natural Science Foundation of China (National Science Foundation of China) 81971674National University of Singapore (NUS) NUHSRO/2021/034/TRP/09/NanomedicineNational University of Singapore (NUS) UHSRO/2023/008/NUSMed/TCE/LOA
6 · The paper itself

Abstract

Constructing organic fluorophosphines, vital drug skeletons, through the direct fluorination of readily available alkyl phosphonates has been impeded due to the intrinsic low electrophilicity of P

Indexed as

Fluorine RadioisotopesHalogenationOrganophosphonatesAnimalsMicePhosphinesPositron-Emission TomographyRadiopharmaceuticalsFluorine-18Fluorine RadioisotopesOrganophosphonatesPhosphinesRadiopharmaceuticals

Identifiers

PMID39609392
PMCPMC11604993

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.