Evidence map›Paper›PMID 39609275›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2025

Bacteria-targeted imaging using vancomycin-based positron emission tomography tracers can distinguish infection from sterile inflammation.

G B Spoelstra, L M Braams, F F A IJpma, M van Oosten, B L Feringa, W Szymanski, P H Elsinga, Jan Maarten van Dijl

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Radiolabeled Antimicrobials for Infection Imaging: A Scoping Review.International journal of molecular sciences · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

G B Spoelstra *Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Hanzeplein 1, Groningen, 9713GZ, The Netherlands.
L M Braams *Department of Medical Microbiology and Infection Prevention, University of Groningen, University Medical Center Groningen, Hanzeplein 1, Groningen, 9713GZ, The Netherlands.
F F A IJpmaDepartment of Trauma Surgery, University of Groningen, University Medical Center Groningen, Hanzeplein 1, Groningen, 9713GZ, The Netherlands.
M van OostenDepartment of Medical Microbiology and Infection Prevention, University of Groningen, University Medical Center Groningen, Hanzeplein 1, Groningen, 9713GZ, The Netherlands.
B L FeringaStratingh Institute for Chemistry, University of Groningen, Nijenborgh 4, Groningen, 9747AG, The Netherlands.
W SzymanskiDepartment of Radiology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, Groningen, 9713GZ, The Netherlands.
P H Elsinga *Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Hanzeplein 1, Groningen, 9713GZ, The Netherlands.
Jan Maarten van Dijl *Department of Medical Microbiology and Infection Prevention, University of Groningen, University Medical Center Groningen, Hanzeplein 1, Groningen, 9713GZ, The Netherlands. j.m.van.dijl01@umcg.nl.ORCID 0000-0002-5688-8438

Funding

Nederlandse Organisatie voor Wetenschappelijk Onderzoek 16895
6 · The paper itself

Abstract

introductionBacterial infections pose major challenges in medicine. To guide effective infection treatment, faster and more accurate diagnostic modalities are needed. Bacteria-targeted molecular imaging can meet these needs. The present study was aimed at the in vivo evaluation of two

methodsThe potential of [

resultsBoth

conclusionVancomycin-based PET is a potentially attractive approach to distinguish Gram-positive bacterial infections from sterile inflammation.

Indexed as

InflammationPositron-Emission TomographyVancomycinAnimalsDiagnosis, DifferentialFemaleFluorodeoxyglucose F18MiceRadioactive TracersRadiopharmaceuticalsStaphylococcal InfectionsStaphylococcus aureusFluorodeoxyglucose F18Radioactive TracersRadiopharmaceuticalsVancomycin18F-vancomycinAntibiotic-based tracerBacterial infection imagingIn vivoMyositisPETVancomycin

Identifiers

PMID39609275
PMCPMC11928434

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.