Evidence map›Paper›PMID 39609172›Full record

ArticlePancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]2024

Development of a core outcome set for recurrent acute and chronic pancreatitis: Results of a Delphi poll.

Lola Rahib, William Salerno, Maisam Abu-El-Haija, Darwin L Conwell, A Jay Freeman, Phil A Hart, Stephen J Pandol, Emily R Perito, Dhiraj Yadav, Tonya M Palermo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Personalizing treatment of pancreatitis-associated chronic pain: the need for an integrated omics approach.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lola RahibMission: Cure, New York, New York, USA.
William SalernoMission: Cure, New York, New York, USA.
Maisam Abu-El-HaijaDivision of Gastroenterology, Hepatology and Nutrition Cincinnati Children's Hospital Medical Center, Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, OH, USA.
Darwin L ConwellUniversity of Kentucky, Lexington, KY, USA.
A Jay FreemanDivision of Gastroenterology, Hepatology and Nutrition, Nationwide Children's Hospital, The Ohio State College of Medicine, Columbus, OH, USA.
Phil A HartDivision of Gastroenterology, Hepatology, and Nutrition, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Stephen J PandolKarsh Division of Gastroenterology and Hepatology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Emily R PeritoDepartment of Pediatrics, University of California, San Francisco, CA, USA.
Dhiraj YadavDivision of Gastroenterology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Tonya M PalermoCenter for Child Health, Behavior and Development, Seattle Children's Research Institute, Seattle, WA, USA. Electronic address: tonya.palermo@seattlechildrens.org.

Funding

University of Kentucky Markey Cancer Center Support Grant ECIA SupplementP30CA177558 · NCI · UNIVERSITY OF KENTUCKY · PI Jennifer F Rogers · 2013 to 2026
$38.3M
Internet-Delivered Pain Self-Management to Reduce Pain and Interference in Chronic PancreatitisR01DK137520 · NIDDK · SEATTLE CHILDREN'S HOSPITAL · PI DARWIN LEWIS CONWELL, Tonya M Palermo · 2023 to 2026
$3.0M
NCI NIH HHS P30 CA177558NIDDK NIH HHS R01 DK137520
6 · The paper itself

Abstract

BACKGROUND/

objectiveRecurrent acute pancreatitis (RAP) and chronic pancreatitis (CP) lack effective therapies. There is no consensus or guidance on which endpoints or outcome measures should be used in clinical trials. This study aimed to develop a core outcome set aligned with both patient and provider priorities for RAP and CP. Utilizing the Outcomes Measures in Rheumatology (OMERACT) framework, a multi-stakeholder approach was adopted to identify and prioritize outcome domains.

methodsA two-round Delphi poll was conducted among four stakeholder groups: adult patients, parents and pediatric patients, adult health care providers and pediatric health care providers. Steering committee consensus further refined the core outcome domains, categorizing them as mandatory, important but optional, or research agenda domains, with full consensus achieved.

resultsPain severity, ability to participate in social roles and activities, pancreatitis related hospitalization/ER visits and acute pancreatitis flare-ups were recommended as mandatory outcome domains for future clinical trials in RAP/CP.

conclusionsUsing the OMERACT framework, we developed a core outcome set for RAP and CP. Future research will focus on identifying validated measures for each domain, facilitating standardized assessments across clinical trials.

Indexed as

Delphi TechniquePancreatitisPancreatitis, ChronicRecurrenceAcute DiseaseAdultConsensusFemaleHumansMaleOutcome Assessment, Health CareChronic pancreatitisCore outcome setsRecurrent acute pancreatitis

Identifiers

PMID39609172
PMCPMC11648530

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.