Evidence map›Paper›PMID 39608399›Full record

ArticleNature2025

Individual variability of neural computations underlying flexible decisions.

Marino Pagan, Vincent D Tang, Mikio C Aoi, Jonathan W Pillow, Valerio Mante, David Sussillo, Carlos D Brody

Abstract read
In one paragraph

Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Article
  2. Cerebellar microcircuits enable robust evidence-based decisions through cortico-cerebellar coupling.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Addressing degeneracy in rodent studies of cognition.Current opinion in neurobiology · 2026
    Review
  10. Article
  11. Article
  12. Dynamical modeling of individual sensory reactivity and habituation learning.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  13. Article
  14. Article
  15. Neural Bases of Collective Social Behavior and Group Interactions across Species.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Review
  16. Article
  17. Article
  18. Article
  19. The geometry of context-dependent biased decisions during learning.bioRxiv : the preprint server for biology · 2026
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marino PaganPrinceton Neuroscience Institute, Princeton, NJ, USA. mpagan@ed.ac.uk.ORCID 0000-0002-4376-0283
Vincent D TangPrinceton Neuroscience Institute, Princeton, NJ, USA.
Mikio C AoiPrinceton Neuroscience Institute, Princeton, NJ, USA.
Jonathan W PillowPrinceton Neuroscience Institute, Princeton, NJ, USA.ORCID 0000-0002-3638-8831
Valerio ManteUniversity of Zurich, Zurich, Switzerland.
David SussilloDepartment of Electrical Engineering, Stanford University, Stanford, CA, USA.
Carlos D BrodyPrinceton Neuroscience Institute, Princeton, NJ, USA. brody@princeton.edu.ORCID 0000-0002-4201-561X

Funding

An experimental platform to investigate the neural mechanisms underlying flexible decision-makingR21MH124383 · NIMH · PRINCETON UNIVERSITY · PI BRODY, CARLOS D · 2021 to 2022
$446k
NIMH NIH HHS R21 MH124383
6 · The paper itself

Abstract

The ability to flexibly switch our responses to external stimuli according to contextual information is critical for successful interactions with a complex world. Context-dependent computations are necessary across many domains

Indexed as

Decision MakingIndividualityModels, NeurologicalNeuronsAnimalsFemaleMaleRatsRats, Long-Evans

Identifiers

PMID39608399
PMCPMC11903320

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.