Evidence map›Paper›PMID 39607923›Full record

ArticleScience (New York, N.Y.)2024

Molecular basis of mRNA delivery to the bacterial ribosome.

Michael W Webster, Adrien Chauvier, Huma Rahil, Andrea Graziadei, Kristine Charles, Nataliya Miropolskaya, Maria Takacs, Charlotte Saint-André, Juri Rappsilber, Nils G Walter and 1 more

Abstract read
In one paragraph

Article in Science (New York, N.Y.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Structure and mechanism of antiphage retron Eco2.Nature structural & molecular biology · 2026
    Article
  7. Suppressor analysis inFrontiers in microbiology · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. State-of-the-Art and Future Directions in Structural Proteomics.Molecular & cellular proteomics : MCP · 2025
    Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Michael W Webster *Department of Integrated Structural Biology, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Illkirch Cedex, France.ORCID 0000-0001-8429-5202
Adrien Chauvier *Single Molecule Analysis Group, Department of Chemistry and Center for RNA Biomedicine, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0003-4473-6194
Huma Rahil *Department of Integrated Structural Biology, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Illkirch Cedex, France.ORCID 0000-0003-2859-2434
Andrea Graziadei *Technische Universität Berlin, Chair of Bioanalytics, Berlin, Germany.ORCID 0000-0001-7709-6002
Kristine CharlesTechnische Universität Berlin, Chair of Bioanalytics, Berlin, Germany.ORCID 0000-0002-1291-2627
Nataliya MiropolskayaDepartment of Integrated Structural Biology, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Illkirch Cedex, France.
Maria TakacsDepartment of Integrated Structural Biology, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Illkirch Cedex, France.ORCID 0000-0001-8616-8418
Charlotte Saint-AndréDepartment of Integrated Structural Biology, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Illkirch Cedex, France.ORCID 0000-0002-7942-525X
Juri RappsilberTechnische Universität Berlin, Chair of Bioanalytics, Berlin, Germany.ORCID 0000-0001-5999-1310
Nils G WalterSingle Molecule Analysis Group, Department of Chemistry and Center for RNA Biomedicine, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0002-7301-1275
Albert WeixlbaumerDepartment of Integrated Structural Biology, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Illkirch Cedex, France.ORCID 0000-0001-9635-3844

Funding

The RNA nanomachines of the gene expression machinery dissected at the single molecule levelR35GM131922 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI NILS G WALTER · 2019 to 2026
$6.9M
NIGMS NIH HHS R35 GM131922
6 · The paper itself

Abstract

Protein synthesis begins with the formation of a ribosome-messenger RNA (mRNA) complex. In bacteria, the small ribosomal subunit (30

Indexed as

Escherichia coliEscherichia coli ProteinsPeptide Chain Initiation, TranslationalProtein BiosynthesisRibosomal ProteinsRibosome Subunits, Small, BacterialRNA, BacterialRNA, MessengerCryoelectron MicroscopyDNA-Directed RNA PolymerasesSingle Molecule ImagingTranscription, GeneticDNA-Directed RNA PolymerasesEscherichia coli ProteinsRibosomal ProteinsRNA, BacterialRNA, Messenger

Identifiers

PMID39607923
PMCPMC13040446

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.