Evidence map›Paper›PMID 39607897›Full record

ArticleThe oncologist2025

Hospital care trajectories of older adults with cancer and the associated clinical profiles.

Charline Jean, Elena Paillaud, Pascaline Boudou-Rouquette, Claudia Martinez-Tapia, Frédéric Pamoukdjian, Meoïn Hagège, Stéphane Bréant, Claire Hassen-Khodja, Pierre-André Natella, Tristan Cudennec and 4 more

Abstract readMulticenter Study
In one paragraph

Article in The oncologist, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Charline JeanUniversité Paris-Est Créteil, Inserm, IMRB U955, 94010 Créteil, France.ORCID 0000-0001-7616-2709
Elena PaillaudUniversité Paris-Est Créteil, Inserm, IMRB U955, 94010 Créteil, France.ORCID 0000-0002-5579-9927
Pascaline Boudou-RouquetteAP-HP, Hôpital Cochin, Service d'Oncologie Médicale, Ariane program, 75014 Paris, France.
Claudia Martinez-TapiaUniversité Paris-Est Créteil, Inserm, IMRB U955, 94010 Créteil, France.
Frédéric PamoukdjianAP-HP, Hôpital Avicenne, Service de Gériatrie, 93000 Bobigny, France.
Meoïn HagègeUniversité Paris-Est Créteil, Inserm, IMRB U955, 94010 Créteil, France.ORCID 0000-0002-5863-8870
Stéphane BréantAP-HP, Pôle Innovation et Données, DSN, 75012 Paris, France.
Claire Hassen-KhodjaAP-HP, Direction de la Recherche Clinique et de l'Innovation, 75012 Paris, France.
Pierre-André NatellaAssistance Publique - Hôpitaux de Paris (AP-HP), Hôpital Henri-Mondor, Service Santé Publique & Unité de Recherche clinique, 94010 Créteil, France.
Tristan CudennecAP-HP, Hôpital Ambroise-Paré, Service de Gériatrie, 92100 Boulogne-Billancourt, France.
Marie LaurentUniversité Paris-Est Créteil, Inserm, IMRB U955, 94010 Créteil, France.
Philippe CailletUniversité Paris-Est Créteil, Inserm, IMRB U955, 94010 Créteil, France.ORCID 0000-0003-3583-6070
Etienne AudureauUniversité Paris-Est Créteil, Inserm, IMRB U955, 94010 Créteil, France.
Florence Canouï-PoitrineUniversité Paris-Est Créteil, Inserm, IMRB U955, 94010 Créteil, France.ORCID 0000-0001-9970-6051

Funding

AP-HP research foundationCanceropôle Ile-de-FranceFrench National Cancer InstituteGerontopôle Ile-de-FranceInstitut National du Cancer, INCa
6 · The paper itself

Abstract

backgroundThe longitudinal hospital care experiences of older adults with cancer, from the treatment decision-making process until their end of life, remain unexplored. We examined the hospital care trajectories of these patients and identified associated clinical determinants. MATERIALS AND

methodsWe linked the ELCAPA multicenter cohort study (patients aged ≥70 with a solid tumor and having been referred for a geriatric assessment between 2012 and 2019) and the Greater Paris University Hospitals' clinical data warehouse. Individual care trajectories, defined as series of consultations, hospital admissions (in day, acute, or rehabilitation units), and emergency room (ER) visits, were clustered using multichannel sequence analysis. Cluster membership determinants were identified among socio-demographic, oncological, and geriatric parameters by logistic regression analysis.

resultsSeven hundred seven patients (median age: 82; metastatic cancer: 45.2%; 10 998 care episodes) were included. Four trajectory clusters were identified: cluster A (n = 149, 21.1%) with in-hospital surgical trajectories, cluster B (n = 198, 28.0%) with outpatient care trajectories with chemotherapy and/or radiotherapy, cluster C (n = 302, 42.7%) without any hospital cancer treatments, and cluster D (n = 58, 8.2%) with mostly chemotherapy and high hospital care consumption. Cluster belonging determinants included metastatic status and cancer site (for cluster A); cognition, mobility, and mood status (unimpaired parameters for cluster B and impaired for cluster C); and younger age (for cluster D).

conclusionsWhile highlighting varied hospital care experiences among older patients with cancer, we found that age remains an independent determinant of chemotherapy-dominant care trajectories.

Indexed as

HospitalizationNeoplasmsAgedAged, 80 and overCohort StudiesFemaleGeriatric AssessmentHumansMalecare trajectoriesclusteringelectronic health recordsgeriatric assessment

Identifiers

PMID39607897
PMCPMC11954495

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.