Evidence map›Paper›PMID 39607896›Full record

ArticleMagnetic resonance in medicine2025

Single breath-hold volumetric lung imaging at 0.55T using stack-of-spiral (SoS) out-in balanced SSFP.

Ye Tian, Nam G Lee, Ziwei Zhao, Alison G Wilcox, Jorge J Nieva, Krishna S Nayak

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Ye TianMing Hsieh Department of Electrical and Computer Engineering, Viterbi School of Engineering, University of Southern Calillrnia, Los Angeles, California, USA.ORCID https://orcid.org/0000-0002-8559-4404
Nam G LeeDepartment of Biomedical Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, California, USA.ORCID https://orcid.org/0000-0001-5462-1492
Ziwei ZhaoMing Hsieh Department of Electrical and Computer Engineering, Viterbi School of Engineering, University of Southern Calillrnia, Los Angeles, California, USA.ORCID https://orcid.org/0000-0003-0281-1141
Alison G WilcoxDepartment of Radiology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Jorge J NievaOncology Division, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Krishna S NayakMing Hsieh Department of Electrical and Computer Engineering, Viterbi School of Engineering, University of Southern Calillrnia, Los Angeles, California, USA.ORCID https://orcid.org/0000-0001-5735-3550

Funding

Volumetric Real-Time MRI at 0.55 TeslaU01HL167613 · NHLBI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Adrienne Campbell, Krishna Shrinivas Nayak · 2023 to 2026
$2.0M
Improved Myocardial Perfusion Assessment using High-Performance Low-Field MRIR21HL159533 · NHLBI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI NAYAK, KRISHNA S · 2022 to 2023
$454k
Division of Computer and Network Systems 1828736NHLBI NIH HHS R21 HL159533NHLBI NIH HHS R21HL159533NHLBI NIH HHS U01 HL167613NHLBI NIH HHS U01HL167613
6 · The paper itself

Abstract

purposeTo develop a robust single breath-hold approach for volumetric lung imaging at 0.55T.

methodA balanced-SSFP (bSSFP) pulse sequence with 3D stack-of-spiral (SoS) out-in trajectory for volumetric lung imaging at 0.55T was implemented. With 2.7× undersampling, the pulse sequence enables imaging during a 17-s breath-hold. Image reconstruction is performed using 3D SPIRiT and 3D l1-Wavelet regularizations. In two healthy volunteers, single breath-hold SoS out-in bSSFP was compared against stack-of-spiral UTE (spiral UTE) and half-radial dual-echo bSSFP (bSTAR), based on signal intensity (SI), blood-lung parenchyma contrast, and image quality. In six patients with pathologies including lung nodules, fibrosis, emphysema, and air trapping, single breath-hold SoS out-in and bSTAR were compared against low-dose computed tomography (LDCT).

resultsSoS out-in bSSFP achieved 2-mm isotropic resolution lung imaging with a single breath-hold duration of 17 s. SoS out-in (2-mm isotropic) provided higher lung parenchyma and blood SI and blood-lung parenchyma contrast compared to spiral UTE (2.4 × 2.4 × 2.5 mm

conclusionSingle breath-hold volumetric lung imaging at 0.55T with 2-mm isotropic spatial resolution is feasible using SoS out-in bSSFP. This approach could be useful for rapid lung disease screening, and in cases where free-breathing respiratory navigated approaches fail.

Indexed as

Breath HoldingImage Processing, Computer-AssistedImaging, Three-DimensionalLungLung DiseasesMagnetic Resonance ImagingAdultAgedAlgorithmsFemaleHealthy VolunteersHumansMaleMiddle AgedTomography, X-Ray Computed0.55 teslabSSFPlung imagingspiral out‐in

Identifiers

PMID39607896
PMCPMC11893024

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.