Evidence map›Paper›PMID 39607567›Full record

ArticlePediatric surgery international2024

Prophylactic surgical drain placement with irrigation reduces abscess formation in patients with severe, uncontained, perforated appendicitis.

Michael A Stellon, Devashish S Joshi, Russell Herberg, Brittany Walker, Jessica Hellner, Kevin M Riggle, Hau D Le

Abstract readMulticenter Study
In one paragraph

Article in Pediatric surgery international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michael A StellonDepartment of Surgery, University of Wisconsin School of Medicine and Public Health, 600 Highland Ave, Madison, WI, 53792, USA.
Devashish S JoshiDepartment of Surgery, University of Wisconsin School of Medicine and Public Health, 600 Highland Ave, Madison, WI, 53792, USA.
Russell HerbergDepartment of Surgery, Gunderson Health, LaCrosse, WI, USA.
Brittany WalkerUniversity of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
Jessica HellnerDepartment of Surgery, University of Wisconsin School of Medicine and Public Health, 600 Highland Ave, Madison, WI, 53792, USA.
Kevin M RiggleDepartment of Surgery, University of Wisconsin School of Medicine and Public Health, 600 Highland Ave, Madison, WI, 53792, USA.
Hau D LeDepartment of Surgery, University of Wisconsin School of Medicine and Public Health, 600 Highland Ave, Madison, WI, 53792, USA. leh@surgery.wisc.edu.

Funding

Training Program in Translational Cardiovascular Science (TPTCS)T32HL007936 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI Lee Lochbaum Eckhardt, Gail A Robertson · 2001 to 2026
$11.6M
Predicting Future Liver Remnant Function and Growth Trajectory Using Novel MR Imaging BiomarkersF32CA284535 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI JOSHI, DEVASHISH · 2023 to 2023
$70k
National Cancer Institute of the National Institutes of Health F32CA284535NCI NIH HHS F32 CA284535NHLBI NIH HHS T32 HL 007936NHLBI NIH HHS T32 HL007936
6 · The paper itself

Abstract

background20-25% of perforated appendicitis cases are complicated by abscess formation. This study assesses whether prophylactic closed-suction surgical drain (SD) placement after irrigation can decrease postoperative abscess formation in patients with extensively contaminated, perforated appendicitis.Affiliations: Journal instruction requires country for affiliations; however, these are missing in all affiliations. Please verify if the provided country names are correct and amend if necessary.They're correct

methodsA multicenter retrospective review was performed on pediatric patients with uncontained perforated appendicitis from January 1, 2020 to August 1, 2023. Limited irrigation was performed. All SDs were oriented towards the pelvis. Data were analyzed in four groups: (G1) SD and irrigation, (G2) only SD, (G3) only irrigation, (G4) neither SD nor irrigation.

resultsOne hundred and fifteen patients (44 in G1, 3 in G2, 21 in G3, 47 in G4) were included. The abscess rate was 5.1% (G1), 33.3% (G2), 33.3% (G3), and 37.0% (G4) (p = 0.001). No interventional radiology (IR) drains were placed in G1 and G2. SD duration was 4.1 ± 2.1 days in G1 and 2.7 ± 0.6 days in G2. IR drain duration was 14 ± 10.7 days in G3 and 8.3 ± 3.9 days in G4 (p < 0.001). There were no significant differences in total length of stay and antibiotic duration.

conclusionsIrrigation with prophylactic SD placement may prevent postoperative abscesses in patients with severe, uncontained, perforated appendicitis, but prospective data are needed.

Indexed as

AppendectomyAppendicitisDrainagePostoperative ComplicationsTherapeutic IrrigationAbdominal AbscessAdolescentChildFemaleHumansMaleRetrospective StudiesAbscessInterventional radiologyPerforated appendicitisProphylactic drain placement

Identifiers

PMID39607567
PMCPMC11980992

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.