Evidence map›Paper›PMID 39607428›Full record

ArticleeLife2024

Modeling corticotroph deficiency with pituitary organoids supports the functional role of

Thi Thom Mac, Teddy Fauquier, Nicolas Jullien, Pauline Romanet, Heather Etchevers, Anne Barlier, Frederic Castinetti, Thierry Brue

Abstract read
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
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  4. Article
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Thi Thom MacAix-Marseille University, INSERM, UMR1251, Marseille Medical Genetics, Institut MarMaRa, Marseille, France.ORCID https://orcid.org/0000-0002-3746-2669
Teddy FauquierAix-Marseille University, INSERM, UMR1251, Marseille Medical Genetics, Institut MarMaRa, Marseille, France.ORCID https://orcid.org/0000-0003-1132-9402
Nicolas JullienAix-Marseille University, CNRS, UMR7051, Institut de NeuroPhysiopathologie, Marseille, France.
Pauline RomanetAix-Marseille University, INSERM, UMR1251, Marseille Medical Genetics, Institut MarMaRa, Marseille, France.
Heather EtcheversAix-Marseille University, INSERM, UMR1251, Marseille Medical Genetics, Institut MarMaRa, Marseille, France.ORCID https://orcid.org/0000-0003-0201-3799
Anne BarlierAix-Marseille University, INSERM, UMR1251, Marseille Medical Genetics, Institut MarMaRa, Marseille, France.
Frederic CastinettiAix-Marseille University, INSERM, UMR1251, Marseille Medical Genetics, Institut MarMaRa, Marseille, France.
Thierry BrueAix-Marseille University, INSERM, UMR1251, Marseille Medical Genetics, Institut MarMaRa, Marseille, France.ORCID https://orcid.org/0000-0001-8482-6691

Funding

AFMTéléthon MOTHARD Project N° 23408Pfizer France ID#88979183
6 · The paper itself

Abstract

Deficient Anterior pituitary with common Variable Immune Deficiency (DAVID) syndrome results from

Indexed as

Cell DifferentiationInduced Pluripotent Stem CellsNF-kappa B p52 SubunitOrganoidsAdrenal InsufficiencyCorticotrophsHumansMutationPituitary GlandNF-kappa B p52 SubunitNFKB2 protein, humanACTH deficiencycommon variable immunodeficiencycorticotroph deficitDAVID syndromedevelopmental biologyhumanOrganoidspituitary developmentpituitary hormone deficitsregenerative medicinestem cells

Identifiers

PMID39607428
PMCPMC11604219

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.