Evidence map›Paper›PMID 39607284›Full record

ArticleImmunology and cell biology2025

RNAi library screening reveals Gβ1, Casein Kinase 2 and ICAP-1 as novel regulators of LFA-1-mediated T cell polarity and migration.

Antje Haap-Hoff, Michael Freeley, Eugene Dempsey, Dara Dunican, Emily Bennett, Denise Triglia, Joanna Skubis-Zegadlo, Anthony Mitchell Davies, Dermot Kelleher, Aideen Long

Abstract read
In one paragraph

Article in Immunology and cell biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Antje Haap-HoffTrinity Translational Medicine Institute & Department of Clinical Medicine, Trinity College Dublin, St James's Hospital, Dublin, Republic of Ireland.
Michael FreeleyTrinity Translational Medicine Institute & Department of Clinical Medicine, Trinity College Dublin, St James's Hospital, Dublin, Republic of Ireland.ORCID 0000-0002-5763-6582
Eugene DempseyTrinity Translational Medicine Institute & Department of Clinical Medicine, Trinity College Dublin, St James's Hospital, Dublin, Republic of Ireland.
Dara DunicanTrinity Translational Medicine Institute & Department of Clinical Medicine, Trinity College Dublin, St James's Hospital, Dublin, Republic of Ireland.
Emily BennettTrinity Translational Medicine Institute & Department of Clinical Medicine, Trinity College Dublin, St James's Hospital, Dublin, Republic of Ireland.
Denise TrigliaTrinity Translational Medicine Institute & Department of Clinical Medicine, Trinity College Dublin, St James's Hospital, Dublin, Republic of Ireland.
Joanna Skubis-ZegadloTrinity Translational Medicine Institute & Department of Clinical Medicine, Trinity College Dublin, St James's Hospital, Dublin, Republic of Ireland.
Anthony Mitchell DaviesTrinity Translational Medicine Institute & Department of Clinical Medicine, Trinity College Dublin, St James's Hospital, Dublin, Republic of Ireland.
Dermot KelleherTrinity Translational Medicine Institute & Department of Clinical Medicine, Trinity College Dublin, St James's Hospital, Dublin, Republic of Ireland.
Aideen LongTrinity Translational Medicine Institute & Department of Clinical Medicine, Trinity College Dublin, St James's Hospital, Dublin, Republic of Ireland.

Funding

Programme for Research in Third Level Institutions (PRTLI) Ireland
6 · The paper itself

Abstract

The α

Indexed as

Casein Kinase IICell MovementCell PolarityLymphocyte Function-Associated Antigen-1RNA InterferenceT-LymphocytesCell LineHumansIntracellular Signaling Peptides and ProteinsCasein Kinase IIIntracellular Signaling Peptides and ProteinsLymphocyte Function-Associated Antigen-1cell migrationcell polarityT cells

Identifiers

PMID39607284
PMCPMC11688611

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.