Evidence map›Paper›PMID 39607155›Full record

ArticleArquivos brasileiros de oftalmologia2024

Neonatal conjunctivitis at a Brazilian tertiary center: the current relevance of Chlamydia trachomatis.

Juliana Mika Kato, Eduardo Ferracioli Oda, Thaisa Silveira Barbosa, Flavia Rossi, Andre Mario Doi, Carolina Dos Santos Lazari, Tatiana Tanaka, Joyce Hisae Yamamoto

Abstract read
In one paragraph

Article in Arquivos brasileiros de oftalmologia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Juliana Mika KatoDepartamento de Oftalmologia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.ORCID 0000-0002-1815-4644
Eduardo Ferracioli OdaDepartamento de Oftalmologia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.ORCID 0000-0002-3993-3794
Thaisa Silveira BarbosaDepartamento de Oftalmologia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.ORCID 0000-0002-7726-3445
Flavia RossiDivisão de Laboratório Central, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.ORCID 0000-0003-2298-1869
Andre Mario DoiDivisão de Laboratório Central, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.ORCID 0000-0002-0722-1880
Carolina Dos Santos LazariDivisão de Laboratório Central, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.ORCID 0000-0002-1418-1880
Tatiana TanakaDepartamento de Oftalmologia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.ORCID 0000-0002-4641-7421
Joyce Hisae YamamotoDepartamento de Oftalmologia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.ORCID 0000-0001-6869-2988

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe microbiology pattern of neonatal conjunctivitis has changed over time, and the incidence of gonococcal conjunctivitis is almost nil. This study aimed to determine the etiology of neonatal conjunctivitis cases referred to a tertiary health center in Brazil.

methodsFrom 2017 to 2020, conjunctival swabs were taken from neonates with clinical signs of conjunctivitis and tested with bacterial culture and polymerase chain reaction for Neisseria gonorrhoeae and Chlamydia trachomatis.

resultsA total of 51 neonates were included in the 3-year study. Chlamydial conjunctivitis was diagnosed in 39 (76.5%) patients, and microbial growth was detected in 13 (25.5%) patients. The most isolated bacterium was Staphylococcus epidermidis (n=6, 11.8%), followed by other coagulase-negative Staphylococcus species (n=4, 7.8%) and S. aureus (n=2, 3.9%). One S. aureus isolate was resistant to oxacillin. There were no cases of gonococcal conjunctivitis. Ten (19.6%) patients showed polymerase chain reaction-negative C. trachomatis and negative bacterial culture test results.

conclusionFindings show that C. trachomatis is the most common pathogen causing neonatal conjunctivitis. The high prevalence of C. trachomatis infection highlights the importance of screening and treating pregnant woman.

Indexed as

Chlamydia InfectionsChlamydia trachomatisTertiary Care CentersAnti-Bacterial AgentsBrazilConjunctivitisConjunctivitis, BacterialFemaleHumansInfant, NewbornMaleNeisseria gonorrhoeaePolymerase Chain ReactionAnti-Bacterial Agents

Identifiers

PMID39607155
PMCPMC12997647

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.