Evidence map›Paper›PMID 39607080›Full record

ArticleEuropean journal of neurology2025

Atrial fibrillation in young stroke patients: Associated factors and outcomes in a nationwide analysis.

Tania Garrido-Hernández, Laura Amaya-Pascasio, Miguel Quesada-López, Antonio Arjona-Padillo, Juan Manuel García-Torrecillas, Patricia Martínez-Sánchez

Abstract read
In one paragraph

Article in European journal of neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tania Garrido-HernándezDepartment of Neurology, Stroke Centre, Torrecárdenas University Hospital, Almería, Spain.ORCID 0009-0008-4902-4755
Laura Amaya-PascasioDepartment of Neurology, Stroke Centre, Torrecárdenas University Hospital, Almería, Spain.
Miguel Quesada-LópezDepartment of Neurology, Stroke Centre, Torrecárdenas University Hospital, Almería, Spain.
Antonio Arjona-PadilloDepartment of Neurology, Stroke Centre, Torrecárdenas University Hospital, Almería, Spain.
Juan Manuel García-TorrecillasDepartment of Emergency Medicine and Biomedical Research Unit, Torrecárdenas University Hospital, Almería, Spain.
Patricia Martínez-SánchezDepartment of Neurology, Stroke Centre, Torrecárdenas University Hospital, Almería, Spain.

Funding

Instituto de Salud Carlos III RD21/0006/0010
6 · The paper itself

Abstract

background and purposeKnowledge about the prevalence of atrial fibrillation (AF) in young stroke patients, as well as its associated factors and outcomes, is scarce. Our objective was to analyse it.

methodsA retrospective analysis of the Spain Nationwide Minimum Basic Data Set (MBDS) (2016-2020), including ischaemic stroke (IS) patients aged 18 and 50 years, was conducted. Multivariate analyses were conducted to identify factors related to AF diagnosis.

resultsAmongst 11,615 young IS patients, 426 (3.7%) had AF. Patients with AF were older (median age 45, interquartile range 42-48 vs. 44, interquartile range 40-47 years, p < 0.001) and displayed more incapacitating symptoms, higher in-hospital complications and were less often discharged home (p < 0.001). Multivariate analyses showed that older age (odds ratio [OR] 1.053, 95% confidence interval [CI] 1.032-1.074), obstructive sleep apnoea (OR 1.508, 95% CI 1.018-2.233), hyperthyroidism (OR 3.741, 95% CI 1.798-7.783), valvular heart disease (OR 6.094, 95% CI 4.261-8.716), congenital (OR 2.386, 95% CI 1.146-4.969) and non-congenital (OR 4.446, 95% CI 3.149-6.278) cardiopathies and heart failure (OR 3.098, 95% CI 1.905-5.037) were independently associated with higher probability of AF, whereas female gender (OR 0.647, 95% CI 0.516-0.812), diabetes mellitus (0.487, 95% CI 0.339-0.699), smoking (OR 0.617, 95% CI 0.501-0.759), patent foramen ovale (OR 0.210, 95% CI 0.111-0.396) and arterial dissection (OR 0.294, 95% CI 0.130-0.668) were associated with a lower probability.

conclusionsIn young IS patients, AF is associated with more in-hospital complications and disabling strokes. These findings emphasize the need to recognize AF in this demographic group, especially in patients with risk factors like hyperthyroidism and cardiomyopathies. Clinicians should assess these risk factors to ensure timely diagnosis and management of AF.

Indexed as

Atrial FibrillationAdolescentAdultAge FactorsFemaleHumansIschemic StrokeMaleMiddle AgedPrevalenceRetrospective StudiesRisk FactorsSpainStrokeYoung Adultatrial fibrillationoutcomerisk factorsstrokeyoung

Identifiers

PMID39607080
PMCPMC11625936

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.